Origin of Life: Chiral Short RNA Chains Capable of Non‐Enzymatic Peptide Bond Formation
Abstract: A semi‐symmetric vestige of an RNA apparatus with stereochemically controlled ribozyme capabilities is embedded and functions as the site of peptide bond formation within all contemporary ribosomes, a finding that is in line with Lahav and Leiserowitz earlier discoveries on stereochemically controlled chemical reactions. As the structure of this semi‐symmetrical self‐folded RNA entity is almost fully conserved in all known ribosomes, it seems to be resilient to evolution, thus hinting at its pre‐biotic origin and hence, suggested by us, to be the protoribosome. Recent studies, described shortly below, demonstrated peptide bond formation by the laboratory‐designed protoribosomes, which supports the notion that a pre‐biotic bonding entity is still functioning in all contemporary ribosomes.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Origin of Life: Chiral Short RNA Chains Capable of Non‐Enzymatic Peptide Bond Formation ; volume:61 ; number:11-12 ; year:2021 ; pages:863-872 ; extent:10
Israel journal of chemistry ; 61, Heft 11-12 (2021), 863-872 (gesamt 10)
- Urheber
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Bose, Tanaya
Fridkin, Gil
Bashan, Anat
Yonath, Ada
- DOI
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10.1002/ijch.202100054
- URN
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urn:nbn:de:101:1-2022021014063703001402
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:30 MESZ
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Beteiligte
- Bose, Tanaya
- Fridkin, Gil
- Bashan, Anat
- Yonath, Ada
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