Long-term follow-up after scleral lens fixation in patients with Marfan syndrome

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Abstract: Background: The dislocation of the crystalline lens is a common finding in patients with Marfan syndrome (MFS). Scleral intraocular lens (IOL) fixation is an accepted treatment method of this complication. To now, no long-term data on scleral IOL fixation in MFS exist.

Methods: We present a retrospective study of 27 eyes of 17 MFS patients that underwent scleral lens fixation at our clinic between 1999 and 2012. These patients are compared to an age- and surgeon-matched group of 31 eyes of 27 patients who underwent the same procedure for reasons other than MFS.

Results: The median age in the MFS group was 35.4 years versus 35.6 years in the non-MFS group. The median follow-up was 4 years for MFS and 3 years for non-MFS. In the MFS group, significantly more IOL-dislocations occurred than compared to the non-MFS group (30% vs. 6.5%, p = 0.02). Retinal detachment occurred in four MFS-eyes compared to three eyes in the non-MFS group. Biometry prediction error was 1.11 diopters (D) for MFS and 1.33 D for non-MFS (p = 0.11). Median BCVA (best-corrected visual acuity, logMAR) was 0.1 in the MFS group versus 0.3 in non-MFS patients.

Conclusion: Scleral lens fixation in MFS patients achieves satisfying visual and refractive outcomes. Our data shows a significantly higher rate of IOL dislocations in patients with MFS. We therefore recommend addressing this complication preoperatively

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
BMC ophthalmology. 17 (2017), 235, DOI 10.1186/s12886-017-0625-x, issn: 1471-2415
IN COPYRIGHT http://rightsstatements.org/page/InC/1.0 rs

Keyword
Marfan-Syndrom
Hornhautchirurgie
Augenheilkunde
Augenkrankheit

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2017
Creator
Contributor

DOI
10.1186/s12886-017-0625-x
URN
urn:nbn:de:bsz:25-freidok-142689
Rights
Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:43 PM CET

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Time of origin

  • 2017

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