Resolving dyskinesias at sustained anti-OCD efficacy by steering of DBS away from the anteromedial STN to the mesencephalic ventral tegmentum – case report
Abstract: Here we describe therapeutic results in a female patient who underwent bilateral slMFB DBS for OCD. During a 35-month long course of stimulation, she suffered from stimulation-induced dyskinesia of her right leg which we interpreted as co-stimulation of the adjacent anteromedial subthalamic nucleus (amSTN). After reprogramming to steer the stimulation away from the amSTN medial into the direction of the mesencephalic ventral tegmentum (MVT which contains the ventral tegmental area, VTA), the dyskinesias disappeared. Remarkably, anti-OCD efficacy in the presented patient was preserved and achieved with a bilateral stimulation which by our imaging study fully avoided the amSTN
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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Acta neurochirurgica. - 164 (2022) , 2303–2307, ISSN: 0942-0940
- Ereignis
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Veröffentlichung
- (wo)
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Freiburg
- (wer)
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Universität
- (wann)
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2022
- Urheber
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Coenen, Volker Arnd
Schläpfer, Thomas
Meyer, Dora
Kilian, Hannah
Spanier, Susanne
Sajonz, Bastian
Reinacher, Peter
Reisert, Marco
- DOI
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10.1007/s00701-022-05206-w
- URN
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urn:nbn:de:bsz:25-freidok-2267815
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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25.03.2025, 13:52 MEZ
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Beteiligte
- Coenen, Volker Arnd
- Schläpfer, Thomas
- Meyer, Dora
- Kilian, Hannah
- Spanier, Susanne
- Sajonz, Bastian
- Reinacher, Peter
- Reisert, Marco
- Universität
Entstanden
- 2022
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