Inactivation of oral biofilms using visible light and water-filtered infrared A radiation and indocyanine green
Abstract: Aim: To investigate the antimicrobial photodynamic therapy (aPDT) of visible light and water-filtered infrared A radiation in combination with indocyanine green (ICG) on planktonic oral microorganisms as well as on oral biofilm. Methods: The irradiation was conducted for 5 min in combination with ICG. Treatment with chlorhexidine served as a positive control. The number of colony forming units and bacterial vitality were quantified. Results: All tested bacterial strains and salivary bacteria were killed at a level of 3log10. The colony forming units of the initial mature oral biofilms were strongly reduced. The high bactericidal effect of aPDT was confirmed by live/dead staining. Conclusion: The aPDT using visible light and water-filtered infrared A radiation and ICG has the potential to treat periodontitis and peri-implantitis
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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Future medicinal chemistry. - 11, 14 (2019) , 1721-1739, ISSN: 1756-8927
- Keyword
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Indocyaningrün
IR-A
Biofilm
- Event
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Veröffentlichung
- (where)
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Freiburg
- (who)
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Universität
- (when)
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2019
- Creator
- DOI
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10.4155/fmc-2018-0522
- URN
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urn:nbn:de:bsz:25-freidok-1512082
- Rights
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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25.03.2025, 1:49 PM CET
Data provider
This object is provided by:
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Burchard, Thomas
- Karygianni, Lamprini
- Hellwig, Elmar
- Follo, Marie
- Wrbas, Karl-Thomas
- Wittmer, Annette
- Vach, Kirstin
- Al-Ahmad, Ali
- Universität
Time of origin
- 2019
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