Nutzen des kapillären PO2 in der Diagnostik von hypoxämischen COPD-Patienten

Hochschulschrift

Abstract: Purpose: To compare arterial (PaO2) with capillary (PcO2) partial pressure of oxygen in hypoxemic COPD patients because capillary blood gas analysis (CBG) is increasingly being used as an alternative to arterial blood gas analysis (ABG) in a non-intensive care unit setting, although the agreement between PcO2 and PaO2 has not been evaluated in hypoxemic COPD patients.
Patients and methods: Bland–Altman comparison of PaO2 and PcO2 served as the primary outcome parameter if PcO2 values were #60 mmHg and the secondary outcome parameter if PcO2 values were #55 mmHg. Pain associated with the measurements was assessed using a 100-mm visual analog scale.

Results: One hundred and two PaO2/PcO2 measurement pairs were obtained. For PcO2 values #60 mmHg, the mean difference between PaO2 and PcO2 was 5.99±6.05 mmHg (limits of agreement: -5.88 to 17.85 mmHg). For PcO2 values #55 mmHg (n=73), the mean difference was 5.33±5.52 mmHg (limits of agreement: -5.48 to 16.15 mmHg). If PaO2 #55 (#60) mmHg was set as the cut-off value, in 20.6% (30.4%) of all patients, long-term oxygen therapy have been unnecessarily prescribed if only PcO2 would have been assessed. ABG was rated as more painful compared with CBG.

Conclusions: PcO2 does not adequately reflect PaO2 in hypoxemic COPD patients, which can lead to a relevant number of unnecessary long-term oxygen therapy prescriptions

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Deutsch
• Anmerkungen: Universität Freiburg, Dissertation, 2019

Klassifikation und Themen

• Schlagwort: Obstruktive Ventilationsstörung ; Atmungsinsuffizienz ; Hypoxämie ; Blutgasanalyse ; Sauerstoff ; Partialdruck ; Medizinisches Gutachten ; Pulmonologie ; Patient ; Diagnostik ; Obstruktive Ventilationsstörung ; Blutgasanalyse ; Obstruktive Ventilationsstörung ; Atmungsinsuffizienz ; Hypoxämie

Beteiligte, Orts- und Zeitangaben

• Ereignis: Veröffentlichung
• (wo): Freiburg
• (wer): Universität
• (wann): 2019
• Urheber: Majorski, Daniel
• Beteiligte Personen und Organisationen: Storre, Jan Hendrik ; Magnet, Friederike Sophie ; Albert-Ludwigs-Universität Freiburg. Medizinische Fakultät

Weitere Informationen

• DOI: 10.6094/UNIFR/150568
• URN: urn:nbn:de:bsz:25-freidok-1505681
• Rechteinformation: Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 25.03.2025, 13:41 MEZ