The PETfold and PETcofold web servers for intra- and intermolecular structures of multiple RNA sequences

Abstract: The function of non-coding RNA genes largely depends on their secondary structure and the interaction with other molecules. Thus, an accurate prediction of secondary structure and RNA–RNA interaction is essential for the understanding of biological roles and pathways associated with a specific RNA gene. We present web servers to analyze multiple RNA sequences for common RNA structure and for RNA interaction sites. The web servers are based on the recent PET (Probabilistic Evolutionary and Thermodynamic) models PETfold and PETcofold , but add user friendly features ranging from a graphical layer to interactive usage of the predictors. Additionally, the web servers provide direct access to annotated RNA alignments, such as the Rfam 10.0 database and multiple alignments of 16 vertebrate genomes with human. The web servers are freely available at: http://rth.dk/resources/petfold

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Nucleic acids research. - 39, suppl (2011) , W107-W111, ISSN: 1362-4962

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2019
Creator
Seemann, Stefan E.
Menzel, Peter
Backofen, Rolf
Gorodkin, Jan
Contributor
Freiburg Research Services

DOI
10.1093/nar/gkr248
URN
urn:nbn:de:bsz:25-freidok-1092173
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:54 PM CET

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Associated

  • Seemann, Stefan E.
  • Menzel, Peter
  • Backofen, Rolf
  • Gorodkin, Jan
  • Freiburg Research Services
  • Universität

Time of origin

  • 2019

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