Clinical Characteristics of Microcystic Macular Edema in Chronic Primary Angle-Closure Glaucoma and Primary Open-Angle Glaucoma Patients
Abstract: Introduction: This study investigated the clinical characteristics of and risk factors for microcystic macular edema (MME) in patients with chronic primary angle-closure glaucoma (CPACG) and primary open-angle glaucoma (POAG). Methods: This retrospective observational study included 1,588 eyes from 926 glaucoma inpatients and analyzed the patients’ basic demographic information, visual field parameters, macular scans, and peripapillary retinal nerve fiber layer thickness. Results: Our findings were that the incidence rate of MME was 3.97% (34/857) in CPACG and 5.88% (43/731) in POAG. MME was predominantly diagnosed at an advanced stage in CPACG (almost 100%) compared to POAG (93.02%). MME was most frequently involved in the inferior (83.12%) quadrant of the peri-macular region in both CPACG and POAG. Risk factors for MME occurrence in CPACG and POAG included lower visual field mean deviation (OR = 1.14, 95%: CI 1.05-1.24, p = 0.003; OR = 1.14, 95% CI: 1.06–1.21, p < 0.001) and younger age (OR = 0.92, 95% CI: 0.88-0.96, p < 0.001; OR = 0.96, 95% CI: 0.93–0.99, p = 0.003), while female sex (OR = 0.30, 95% CI: 0.11–0.84, p = 0.022) reduced the MME occurrence in POAG. Conclusion: MME could develop in both CPACG and POAG patients, occurring earlier in POAG. The inferior peri-macular region is commonly affected. Younger age and poorer visual field are risk factors for MME in glaucoma patients.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Clinical Characteristics of Microcystic Macular Edema in Chronic Primary Angle-Closure Glaucoma and Primary Open-Angle Glaucoma Patients ; volume:67 ; number:1 ; year:2024 ; pages:145-153 ; extent:9
Ophthalmic research ; 67, Heft 1 (2024), 145-153 (gesamt 9)
- Creator
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Xiao, Hui
Liu, Yuan
Guo, Ni
Jin, Ling
Wang, Zhenyu
Lin, Shufen
Lin, Yixiu
Zheng, Shaoyang
Tan, Yuheng
Luo, Nachuan
Liu, Xing
Zuo, Chengguo
- DOI
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10.1159/000535900
- URN
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urn:nbn:de:101:1-2406060158124.961413586532
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 11:02 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Xiao, Hui
- Liu, Yuan
- Guo, Ni
- Jin, Ling
- Wang, Zhenyu
- Lin, Shufen
- Lin, Yixiu
- Zheng, Shaoyang
- Tan, Yuheng
- Luo, Nachuan
- Liu, Xing
- Zuo, Chengguo
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