PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1476-5594

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence ; day:23 ; month:5 ; year:2018 ; pages:1-13
Oncogene ; (23.5.2018), 1-13

Creator: Klein, Mary E.

Contributor: Dickson, Mark A.
Antonescu, Cristina
Qin, Li-Xuan
Dooley, Scott J.
Barlas, Afsar
Manova, Katia
Schwartz, Gary K.
Crago, Aimee M.
Singer, Samuel
Koff, Andrew
Tap, William D.
SpringerLink (Online service)

DOI: 10.1038/s41388-018-0332-y

URN: urn:nbn:de:101:1-2018080123075190451598

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:38 AM CEST

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Associated

Klein, Mary E.
Dickson, Mark A.
Antonescu, Cristina
Qin, Li-Xuan
Dooley, Scott J.
Barlas, Afsar
Manova, Katia
Schwartz, Gary K.
Crago, Aimee M.
Singer, Samuel
Koff, Andrew
Tap, William D.
SpringerLink (Online service)

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PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence

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Other Objects (12)

CDK4 inhibition diminishes p53 activation by MDM2 antagonists

Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Overdiagnosis of atypical lipomatous tumors/well-differentiated liposarcomas by morphological diagnosis using only HE stained specimens: a case–control study with MDM2/CDK4 immunostaining and MDM2/CDK4 fluorescence in situ hybridization

Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup

CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma

Molecular pathways of senescence regulate placental structure and function

Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy

Low-Grade Uterine Adenosarcoma with Overexpression of MDM2 and CDK4 by Immunohistochemistry: A Case Report and Literature Review

Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53

Cellular senescence in the response of HR+ breast cancer to radiotherapy and CDK4/6 inhibitors

Npl3 stabilizes R-loops at telomeres to regulate replicative senescence

CDK4 inhibition diminishes p53 activation by MDM2 antagonists

Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Overdiagnosis of atypical lipomatous tumors/well-differentiated liposarcomas by morphological diagnosis using only HE stained specimens: a case–control study with MDM2/CDK4 immunostaining and MDM2/CDK4 fluorescence in situ hybridization

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Low-Grade Uterine Adenosarcoma with Overexpression of MDM2 and CDK4 by Immunohistochemistry: A Case Report and Literature Review

Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53

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CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma

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Cellular senescence in the response of HR+ breast cancer to radiotherapy and CDK4/6 inhibitors

Npl3 stabilizes R-loops at telomeres to regulate replicative senescence

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