CDK4 inhibition diminishes p53 activation by MDM2 antagonists

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2041-4889

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: CDK4 inhibition diminishes p53 activation by MDM2 antagonists ; volume:9 ; number:9 ; day:11 ; month:9 ; year:2018 ; pages:1-16 ; date:9.2018
Cell death & disease ; 9, Heft 9 (11.9.2018), 1-16, 9.2018

Creator: Sriraman, Anusha

Contributor: Dickmanns, Antje
Najafova, Zeynab
Johnsen, Steven A.
Dobbelstein, Matthias
SpringerLink (Online service)

DOI: 10.1038/s41419-018-0968-0

URN: urn:nbn:de:101:1-2018102814500845316868

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 11:01 AM CEST

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Sriraman, Anusha
Dickmanns, Antje
Najafova, Zeynab
Johnsen, Steven A.
Dobbelstein, Matthias
SpringerLink (Online service)

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Mad1 destabilizes p53 by preventing PML from sequestering MDM2

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CDK4 inhibition diminishes p53 activation by MDM2 antagonists

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Other Objects (12)

Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists

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Evolution of the p53-MDM2 pathway

Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas

Small-Molecule Inhibitors of p53-MDM2 interactions

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Serumantikörper gegen die Proteine p53, mdm2 und p21-waf1 und Nachweis der Proteine p53 und mdm2 in menschlichen Tumorgeweben

Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials

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Overdiagnosis of atypical lipomatous tumors/well-differentiated liposarcomas by morphological diagnosis using only HE stained specimens: a case–control study with MDM2/CDK4 immunostaining and MDM2/CDK4 fluorescence in situ hybridization

Mad1 destabilizes p53 by preventing PML from sequestering MDM2

Stress-specific response of the p53-Mdm2 feedback loop

Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists

NMR high resolution spectroscopy and X-ray crystallography for development of MDM2/X-p53 interaction antagonists

Evolution of the p53-MDM2 pathway

Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas

Small-Molecule Inhibitors of p53-MDM2 interactions

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Serumantikörper gegen die Proteine p53, mdm2 und p21-waf1 und Nachweis der Proteine p53 und mdm2 in menschlichen Tumorgeweben

Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials

NAT 10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2

Overdiagnosis of atypical lipomatous tumors/well-differentiated liposarcomas by morphological diagnosis using only HE stained specimens: a case–control study with MDM2/CDK4 immunostaining and MDM2/CDK4 fluorescence in situ hybridization

Mad1 destabilizes p53 by preventing PML from sequestering MDM2

Stress-specific response of the p53-Mdm2 feedback loop

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NMR high resolution spectroscopy and X-ray crystallography for development of MDM2/X-p53 interaction antagonists

Evolution of the p53-MDM2 pathway

Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas

Small-Molecule Inhibitors of p53-MDM2 interactions

Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype

Serumantikörper gegen die Proteine p53, mdm2 und p21-waf1 und Nachweis der Proteine p53 und mdm2 in menschlichen Tumorgeweben

Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials

NAT 10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2

Overdiagnosis of atypical lipomatous tumors/well-differentiated liposarcomas by morphological diagnosis using only HE stained specimens: a case–control study with MDM2/CDK4 immunostaining and MDM2/CDK4 fluorescence in situ hybridization

Mad1 destabilizes p53 by preventing PML from sequestering MDM2

Stress-specific response of the p53-Mdm2 feedback loop

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