Retinal vessel volume reference database derived from volume-rendered optical coherence tomography angiography

to connected objects

Abstract: Optical coherence tomography angiography (OCTA) enables three-dimensional reconstruction of the functional blood vessels in the retina. Therefore, it enables the quantification of 3D retinal vessel parameters such as surface area and vessel volume. In spite of the widespread use of OCTA, no representative volume-rendered vessel volume (VV) data are published to date. In this study, OCTA 3 × 3 mm macular cubes were processed with volume-rendering techniques to measure VV in 203 eyes from 107 healthy volunteers. Generalized linear models (GLM) were constructed to assess the impact of age, gender, visual acuity (VA), spherical equivalent (SE), and axial length (AL) on VV. Overall mean VV was 0.23 ± 0.05mm3. Age and axial length showed a negative correlation with VV. However, GLM model analysis found that AL exerted the most pronounced influence on VV. No statistically significant associations were identified between gender or between left and right eyes. This is the first study to assess 3D OCTA VV and its naturally occurring variations in a large series of healthy subjects. It offers novel insights into the characterization of normal retinal vascular anatomy in healthy individuals, contributing to a valuable reference for future research in this field

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Scientific reports. - 14, 1 (2024) , 2721, ISSN: 2045-2322

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2024
Creator
Feu-Basilio, Silvia
Maloca, Peter M.
Hasler, Pascal W.
Scholl, Hendrik Peter Nicolas
Marin-Martinez, Sara
Rosinés-Fonoll, Josep
Suarez-Valero, Xavier
Reich, Michael
Lange, Clemens
Egan, Catherine
Zweifel, Sandrine A.
Tufail, Adnan
Spaide, Richard F.
Zarranz-Ventura, Javier

DOI
10.1038/s41598-024-53000-8
URN
urn:nbn:de:bsz:25-freidok-2440299
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:46 PM CET

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Show original at data provider

Associated

Time of origin

  • 2024

Other Objects (12)

Reference database of total retinal vessel surface area derived from volume-rendered optical coherence tomography angiography

Reference database of total retinal vessel surface area derived from volume-rendered optical coherence tomography angiography

Reduced Retinal Blood Vessel Densities Measured by Optical Coherence Tomography Angiography in Keratoconus Patients Are Negatively Correlated with Keratoconus Severity

Reduced Retinal Blood Vessel Densities Measured by Optical Coherence Tomography Angiography in Keratoconus Patients Are Negatively Correlated with Keratoconus Severity

Comparison of current optical coherence tomography angiography methods in imaging retinal hemangioblastomas

Comparison of current optical coherence tomography angiography methods in imaging retinal hemangioblastomas

OCT-Angiography reveals reduced vessel density in the deep retinal plexus of CADASIL patients

OCT-Angiography reveals reduced vessel density in the deep retinal plexus of CADASIL patients

Novel insights into retinal neovascularization secondary to central serous chorioretinopathy using 3D optical coherence tomography angiography

Novel insights into retinal neovascularization secondary to central serous chorioretinopathy using 3D optical coherence tomography angiography

OCT angiography in retinal and macular diseases

Aufsatzsammlung

OCT angiography in retinal and macular diseases

Clinical applications of optical coherence tomography angiography

Clinical applications of optical coherence tomography angiography

The apply of spectral domain optical coherence tomography in retinal vessel assessment of diabetic retinopathy

Hochschulschrift

The apply of spectral domain optical coherence tomography in retinal vessel assessment of diabetic retinopathy

Optical coherence tomography angiography–navigated laser photocoagulation of retinal hemangioblastomas in patients with von Hippel–Lindau disease

Optical coherence tomography angiography–navigated laser photocoagulation of retinal hemangioblastomas in patients with von Hippel–Lindau disease

Retinal vessel analyzer (RVA) - design and function

Retinal vessel analyzer (RVA) - design and function

Central retinal thickness und central retinal volume in der Rezidiverkennung der neovaskulären altersabhängigen Makuladegeneration

Hochschulschrift

Central retinal thickness und central retinal volume in der Rezidiverkennung der neovaskulären altersabhängigen Makuladegeneration

Changes in retinal flow density measured by optical coherence tomography angiography in patients with carotid artery stenosis after carotid endarterectomy

Changes in retinal flow density measured by optical coherence tomography angiography in patients with carotid artery stenosis after carotid endarterectomy

Related objects