175 Years of Bilirubin Testing: Ready for Point‐of‐Care?

Abstract: Bilirubin is first detected in blood in 1847 and since then has become one of the most widely used biomarkers for liver disease. Clinical routine bilirubin testing is performed at the hospital laboratory, and the gold standard colorimetric test is prone to interferences. The absence of a bedside test for bilirubin delays critical clinical decisions for patients with liver disease. This clinical care gap has motivated the development of a new generation of bioengineered point‐of‐care bilirubin assays. In this Perspective, recently developed bilirubin assays are critically discussed, and their translational potential evaluated.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
175 Years of Bilirubin Testing: Ready for Point‐of‐Care? ; day:10 ; month:04 ; year:2023 ; extent:8
Advanced healthcare materials ; (10.04.2023) (gesamt 8)

Creator
Guirguis, Natalie
Bertrand, Antoine‐Xavier
Rose, Christopher F.
Matoori, Simon

DOI
10.1002/adhm.202203380
URN
urn:nbn:de:101:1-2023041015075954865785
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:49 AM CEST

Data provider

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Associated

  • Guirguis, Natalie
  • Bertrand, Antoine‐Xavier
  • Rose, Christopher F.
  • Matoori, Simon

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