Multiplexed point-of-care testing – xPOCT

Abstract: Multiplexed point-of-care testing (xPOCT), which is simultaneous on-site detection of different analytes from a single specimen, has recently gained increasing importance for clinical diagnostics, with emerging applications in resource-limited settings (such as in the developing world, in doctors’ offices, or directly at home). Nevertheless, only single-analyte approaches are typically considered as the major paradigm in many reviews of point-of-care testing. Here, we comprehensively review the present diagnostic systems and techniques for xPOCT applications. Different multiplexing technologies (e.g., bead- or array-based systems) are considered along with their detection methods (e.g., electrochemical or optical). We also address the unmet needs and challenges of xPOCT. Finally, we critically summarize the in-field applicability and the future perspectives of the presented approaches

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Trends in biotechnology. - 35, 8 (2017) , 728-742, ISSN: 1879-3096

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2019
Creator
Contributor

DOI
10.1016/j.tibtech.2017.03.013
URN
urn:nbn:de:bsz:25-freidok-1381102
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:33 AM CEST

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Time of origin

  • 2019

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