Functional reorganization in obstructive sleep apnoea and insomnia: a systematic review of the resting-state fMRI

Abstract: Functional neuroimaging techniques have accelerated progress in the study of sleep disorders. Considering the striking prevalence of these disorders in the general population, however, as well as their strong bidirectional relationship with major neuropsychiatric disorders, including major depressive disorder, their numbers are still surprisingly low. This review examines the contribution of resting state functional MRI to current understanding of two major sleep disorders, insomnia disorder and obstructive sleep apnoea. An attempt is made to learn from parallels of previous resting state functional neuroimaging findings in major depressive disorder. Moreover, shared connectivity biomarkers are suggested for each of the sleep disorders. Taken together, despite some inconsistencies, the synthesis of findings to date highlights the importance of the salience network in hyperarousal and affective symptoms in insomnia. Conversely, dysfunctional connectivity of the posterior default mode network appears to underlie cognitive and depressive symptoms of obstructive sleep apnoea

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch
Anmerkungen
Neuroscience & biobehavioral reviews. - 77 (2017) , 219-231, ISSN: 1873-7528

Ereignis
Veröffentlichung
(wo)
Freiburg
(wer)
Universität
(wann)
2019
Urheber
Khazaie, Habibolah
Veronese, Mattia
Noori, Khadijeh
Emamian, Farnoosh
Zarei, Mojtaba
Ashkan, Keyoumars
Leschziner, Guy
Eickhoff, Claudia R.
Eickhoff, Simon B.
Morrell, Mary J.
Osorio, Ricardo S.
Spiegelhalder, Kai
Tahmasian, Masoud
Rosenzweig, Ivana
Beteiligte Personen und Organisationen

DOI
10.1016/j.neubiorev.2017.03.013
URN
urn:nbn:de:bsz:25-freidok-1400706
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:38 MESZ

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Beteiligte

Entstanden

  • 2019

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