Differences in hypothalamic–pituitary–adrenal axis functioning among children with ADHD predominantly inattentive and combined types

Abstract: Some evidence suggests that the HPA axis may be dysfunctional in children with attention-deficit/ hyperactivity disorder (ADHD). The aim of this study was to investigate whether a different pattern of HPA axis activity is found between the inattentive (I) and combined (C) subtypes of ADHD, in comparison with healthy control children. A total of 100 prepubertal subjects [52 children with ADHD combined type (ADHD-C), 23 children with ADHD predominantly inattentive type (ADHD-I), and 25 healthy control subjects] were studied. The effects of stress were studied by comparing cortisol responses to a psychosocial stressor, consisting of a public speaking task. Children with ADHD-I showed an elevated cortisol response to the psychosocial stressor, in contrast to children with ADHD-C who showed a blunted cortisol response to the psychosocial stressor. When a distinction was made between responders and non-responders (a subject was classified as a responder when there was an increase in cort

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch
Anmerkungen
Postprint
begutachtet (peer reviewed)
In: European Child & Adolescent Psychiatry ; 18 (2009) 9 ; 543-553

Ereignis
Veröffentlichung
(wo)
Mannheim
(wann)
2009
Urheber
West, Dirk
Claes, Stephan
Deboutte, Dirk

DOI
10.1007/s00787-009-0011-1
URN
urn:nbn:de:0168-ssoar-202684
Rechteinformation
Open Access unbekannt; Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
25.03.2025, 13:52 MEZ

Datenpartner

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Beteiligte

  • West, Dirk
  • Claes, Stephan
  • Deboutte, Dirk

Entstanden

  • 2009

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