Bioreactors: A Regenerative Approach to Skeletal Muscle Engineering for Repair and Replacement

Engineering skeletal muscle tissue is crucial for the repair and replacement of damaged or dysfunctional muscle. Despite numerous studies emphasizing the significance of skeletal muscle engineering, challenges persist in effectively replacing or repairing large muscle sections in vivo. Bioreactors that facilitate the rapid expansion of muscle precursor cells present a promising solution for addressing extensive muscle loss. Specifically, bioreactors that mimic the native microenvironment of muscle tissue can induce biomimetic stimuli, selectively promoting the expansion of muscle precursors with optimal myo‐regenerative potential. In this review, the advancements made in utilizing bioreactors to enhance the myo‐regenerative phenotype of cells for skeletal muscle engineering are highlighted.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Bioreactors: A Regenerative Approach to Skeletal Muscle Engineering for Repair and Replacement ; day:11 ; month:09 ; year:2024 ; extent:16
Advanced nanoBiomed research ; (11.09.2024) (gesamt 16)

Urheber
Williamson, Alysha
Khoshmanesh, Khashayar
Pirogova, Elena
Yang, Peiqi
Snow, Finn
Williams, Richard
Quigley, Anita
Kapsa, Rob M. I.

DOI
10.1002/anbr.202400030
URN
urn:nbn:de:101:1-2409121404503.940833987302
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:33 MESZ

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Beteiligte

  • Williamson, Alysha
  • Khoshmanesh, Khashayar
  • Pirogova, Elena
  • Yang, Peiqi
  • Snow, Finn
  • Williams, Richard
  • Quigley, Anita
  • Kapsa, Rob M. I.

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