Bioreactors: A Regenerative Approach to Skeletal Muscle Engineering for Repair and Replacement

Engineering skeletal muscle tissue is crucial for the repair and replacement of damaged or dysfunctional muscle. Despite numerous studies emphasizing the significance of skeletal muscle engineering, challenges persist in effectively replacing or repairing large muscle sections in vivo. Bioreactors that facilitate the rapid expansion of muscle precursor cells present a promising solution for addressing extensive muscle loss. Specifically, bioreactors that mimic the native microenvironment of muscle tissue can induce biomimetic stimuli, selectively promoting the expansion of muscle precursors with optimal myo‐regenerative potential. In this review, the advancements made in utilizing bioreactors to enhance the myo‐regenerative phenotype of cells for skeletal muscle engineering are highlighted.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Bioreactors: A Regenerative Approach to Skeletal Muscle Engineering for Repair and Replacement ; day:11 ; month:09 ; year:2024 ; extent:16 ; Advanced nanoBiomed research ; (11.09.2024) (gesamt 16)

Contributors, Places and Time

• Creator: Williamson, Alysha ; Khoshmanesh, Khashayar ; Pirogova, Elena ; Yang, Peiqi ; Snow, Finn ; Williams, Richard ; Quigley, Anita ; Kapsa, Rob M. I.

Further information

• DOI: 10.1002/anbr.202400030
• URN: urn:nbn:de:101:1-2409121404503.940833987302
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:33 AM CEST