Biopolymer‐Based Multilayer Microparticles for Probiotic Delivery to Colon

Abstract: The potential health benefits of probiotics may not be realized because of the substantial reduction in their viability during food storage and gastrointestinal transit. Microencapsulation has been successfully utilized to improve the resistance of probiotics to critical conditions. Owing to the unique properties of biopolymers, they have been prevalently used for microencapsulation of probiotics. However, majority of microencapsulated products only contain a single layer of protection around probiotics, which is likely to be inferior to more sophisticated approaches. This review discusses emerging methods for the multilayer encapsulation of probiotic using biopolymers. Correlations are drawn between fabrication techniques and the resultant microparticle properties. Subsequently, multilayer microparticles are categorized based on their layer designs. Recent reports of specific biopolymeric formulations are examined regarding their physical and biological properties. In particular, animal models of gastrointestinal transit and disease are highlighted, with respect to trials of multilayer microencapsulated probiotics. To conclude, novel materials and approaches for fabrication of multilayer structures are highlighted.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Biopolymer‐Based Multilayer Microparticles for Probiotic Delivery to Colon ; day:03 ; month:03 ; year:2022 ; extent:25
Advanced healthcare materials ; (03.03.2022) (gesamt 25)

Creator
Talebian, Sepehr
Schofield, Timothy
Valtchev, Peter
Schindeler, Aaron
Kavanagh, John M.
Adil, Qayyum
Dehghani, Fariba

DOI
10.1002/adhm.202102487
URN
urn:nbn:de:101:1-2022030414071634958467
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:20 AM CEST

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Associated

  • Talebian, Sepehr
  • Schofield, Timothy
  • Valtchev, Peter
  • Schindeler, Aaron
  • Kavanagh, John M.
  • Adil, Qayyum
  • Dehghani, Fariba

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