One-pot synthesis of β-amino carbonyl compounds catalyzed silica supported phenylphosphinic acid

Abstract: A simple and facile synthesis of β-amino carbonyl compounds was developed by the one-pot condensation of cyclohexanone, aromatic aldehydes and anilines at 25°C in the presence of silica supported phenylphosphinic acid. β-Amino carbonyl compounds were obtained in moderate to good yields and reasonable diastereoselectivities. This method has the advantages of short reaction time, mild reaction conditions, reusable catalyst, cost efficiency and environment friendly. In addition, acetophenone and aliphatic ketones as reactants were investigated.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
One-pot synthesis of β-amino carbonyl compounds catalyzed silica supported phenylphosphinic acid ; volume:4 ; number:1 ; year:2015 ; pages:11-15 ; extent:5
Green processing & synthesis ; 4, Heft 1 (2015), 11-15 (gesamt 5)

Creator
Liu, Di
Zhang, Jingwei
Zhang, Chi
Kou, Xiaoyan

DOI
10.1515/gps-2014-0077
URN
urn:nbn:de:101:1-2501120314594.037140634932
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:36 AM CEST

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Associated

  • Liu, Di
  • Zhang, Jingwei
  • Zhang, Chi
  • Kou, Xiaoyan

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