Solid‐in‐oil nanodispersions for transdermal drug delivery systems

Abstract: Transdermal administration of drugs has advantages over conventional oral administration or administration using injection equipment. The route of administration reduces the opportunity for drug evacuation before systemic circulation, and enables long‐lasting drug administration at a modest body concentration. In addition, the skin is an attractive route for vaccination, because there are many immune cells in the skin. Recently, solid‐in‐oil nanodisperison (S/O) technique has demonstrated to deliver cosmetic and pharmaceutical bioactives efficiently through the skin. S/O nanodispersions are nanosized drug carriers designed to overcome the skin barrier. This review discusses the rationale for preparation of efficient and stable S/O nanodispersions, as well as application examples in cosmetic and pharmaceutical materials including vaccines. Drug administration using a patch is user‐friendly, and may improve patient compliance. The technique is a potent transcutaneous immunization method without needles.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Solid‐in‐oil nanodispersions for transdermal drug delivery systems ; volume:11 ; number:11 ; year:2016 ; pages:1375-1385 ; extent:11 ; Biotechnology journal ; 11, Heft 11 (2016), 1375-1385 (gesamt 11)

Contributors, Places and Time

• Creator: Kitaoka, Momoko ; Wakabayashi, Rie ; Kamiya, Noriho ; Goto, Masahiro

Further information

• DOI: 10.1002/biot.201600081
• URN: urn:nbn:de:101:1-2022111405152096863108
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:23 AM CEST