Solid‐in‐oil nanodispersions for transdermal drug delivery systems

Abstract: Transdermal administration of drugs has advantages over conventional oral administration or administration using injection equipment. The route of administration reduces the opportunity for drug evacuation before systemic circulation, and enables long‐lasting drug administration at a modest body concentration. In addition, the skin is an attractive route for vaccination, because there are many immune cells in the skin. Recently, solid‐in‐oil nanodisperison (S/O) technique has demonstrated to deliver cosmetic and pharmaceutical bioactives efficiently through the skin. S/O nanodispersions are nanosized drug carriers designed to overcome the skin barrier. This review discusses the rationale for preparation of efficient and stable S/O nanodispersions, as well as application examples in cosmetic and pharmaceutical materials including vaccines. Drug administration using a patch is user‐friendly, and may improve patient compliance. The technique is a potent transcutaneous immunization method without needles.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Solid‐in‐oil nanodispersions for transdermal drug delivery systems ; volume:11 ; number:11 ; year:2016 ; pages:1375-1385 ; extent:11 ; Biotechnology journal ; 11, Heft 11 (2016), 1375-1385 (gesamt 11)

Beteiligte, Orts- und Zeitangaben

• Urheber: Kitaoka, Momoko ; Wakabayashi, Rie ; Kamiya, Noriho ; Goto, Masahiro

Weitere Informationen

• DOI: 10.1002/biot.201600081
• URN: urn:nbn:de:101:1-2022111405152096863108
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 15.08.2025, 07:23 MESZ