Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1476-4679

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition ; volume:24 ; number:9 ; day:12 ; month:9 ; year:2022 ; pages:1407-1421 ; date:9.2022
Nature cell biology ; 24, Heft 9 (12.9.2022), 1407-1421, 9.2022

Creator: Figlia, Gianluca
Müller, Sandra
Hertle, Anna M.
Kleber, Susanne
Roiuk, Mykola
Quast, Jan-Philipp
ten Bosch, Nora
Carvajal Ibáñez, Damián
Mauceri, Daniela
Martín-Villalba, Ana
Teleman, Aurelio A.

Contributor: SpringerLink (Online service)

DOI: 10.1038/s41556-022-00977-x

URN: urn:nbn:de:101:1-2022120309443663595079

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:34 AM CEST

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Associated

Figlia, Gianluca
Müller, Sandra
Hertle, Anna M.
Kleber, Susanne
Roiuk, Mykola
Quast, Jan-Philipp
ten Bosch, Nora
Carvajal Ibáñez, Damián
Mauceri, Daniela
Martín-Villalba, Ana
Teleman, Aurelio A.
SpringerLink (Online service)

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Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

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Other Objects (12)

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 signaling in hepatic lipid metabolism

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

Esterase D stabilizes FKBP25 to suppress mTORC1

mTORC1 pathway activity biases cell fate choice

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 signaling in hepatic lipid metabolism

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

Esterase D stabilizes FKBP25 to suppress mTORC1

mTORC1 pathway activity biases cell fate choice

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 signaling in hepatic lipid metabolism

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

Esterase D stabilizes FKBP25 to suppress mTORC1

mTORC1 pathway activity biases cell fate choice

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