Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2041-1723

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction ; volume:9 ; number:1 ; day:19 ; month:10 ; year:2018 ; pages:1-14 ; date:12.2018
Nature Communications ; 9, Heft 1 (19.10.2018), 1-14, 12.2018

Classification: Biowissenschaften, Biologie

Creator: Pal, Rituraj

Contributor: Palmieri, Michela
Chaudhury, Arindam
Klisch, Tiemo Jürgen
di Ronza, Alberto
Neilson, Joel R.
Rodney, George G.
Sardiello, Marco
SpringerLink (Online service)

DOI: 10.1038/s41467-018-06844-4

URN: urn:nbn:de:101:1-2018112022333750081217

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:53 AM CEST

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Associated

Pal, Rituraj
Palmieri, Michela
Chaudhury, Arindam
Klisch, Tiemo Jürgen
di Ronza, Alberto
Neilson, Joel R.
Rodney, George G.
Sardiello, Marco
SpringerLink (Online service)

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A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

Coupling of spatial and GTPase cycle of Rheb enables growth factor signaling to mTORC1

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

mTORC1 signaling in hepatic lipid metabolism

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Hochschulschrift

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

Coupling of spatial and GTPase cycle of Rheb enables growth factor signaling to mTORC1

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

mTORC1 signaling in hepatic lipid metabolism

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Hochschulschrift

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

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Src regulates amino acid-mediated mTORC1 activation by disrupting GATOR1-Rag GTPase interaction

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Other Objects (12)

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

Coupling of spatial and GTPase cycle of Rheb enables growth factor signaling to mTORC1

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

mTORC1 signaling in hepatic lipid metabolism

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

Coupling of spatial and GTPase cycle of Rheb enables growth factor signaling to mTORC1

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

mTORC1 signaling in hepatic lipid metabolism

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids

Role of the Rag GTPases in Amino Acid sensing and mTORC1 signaling

Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

Coupling of spatial and GTPase cycle of Rheb enables growth factor signaling to mTORC1

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

mTORC1 signaling in hepatic lipid metabolism

Macropinocytosis, mTORC1 and cellular growth control

mTORC1 controls long-term memory retrieval

Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1

Nutrient-driven mTORC1 signaling in developmental angiogenesis

Relationship of mTORC1 and ferroptosis in tumors

mTORC1 accelerates retinal development via the immunoproteasome

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