Ion Exchange Controlled Drug Release from Polymerized Ionic Liquids
Abstract: In this work ion functionalized hydrogels as potent drug delivery systems are presented. The ion functionalization of the hydrogel enables the retention of ionic drug molecules and thus a reduction of burst release effects. Timolol maleate in combination with polymerized anionic 3‐sulfopropylmethacrylate potassium and ibuprofen combined with cationic poly‐[2‐(methacryloyloxy) ethyl] trimethylammonium chloride are investigated in respect to their drug release profile. The results are showing an ion exchange depending release behavior instead of a diffusion‐controlled drug release as it is known from common drug delivery systems. Furthermore, the suitability of such hydrogels for standard methods for sterilization is investigated.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Ion Exchange Controlled Drug Release from Polymerized Ionic Liquids ; volume:20 ; number:9 ; year:2020 ; extent:9
Macromolecular bioscience ; 20, Heft 9 (2020) (gesamt 9)
- Urheber
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Claus, Johanna
Eickner, Thomas
Grabow, Niels
Kragl, Udo
Oschatz, Stefan
- DOI
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10.1002/mabi.202000152
- URN
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urn:nbn:de:101:1-2022062614185411513487
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:27 MESZ
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Beteiligte
- Claus, Johanna
- Eickner, Thomas
- Grabow, Niels
- Kragl, Udo
- Oschatz, Stefan
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