5-HTT genotype and inertia of negative affect in adolescents and young adults from the general population
Abstract: The study aims to replicate the previous found association of 5-HTTLPR and inertia of negative affect in daily life of adolescents and young adults. Data of 877 adolescents (aged 14–21 years) of the Behavior and Mind Health (BeMIND) study (epidemiological cohort study, Dresden, Germany) were genotyped for 5-HTTLPR/rs25531, grouped into SS/SLG/SLA/LGLA/LGLG vs. LALA, and provided ratings on negative affect items, depression and anxiety (Patient-Reported Outcomes Measurement Information System) eight times a day over 4 days. Multilevel regression models did not reveal an association of 5-HTTLPR genotype and inertia of negative affect, nor associations with inertia of anxiety or depression. Inertia of negative affect seems not to be a psychological mechanism through which 5-HTTLPR acts on psychopathology
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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Journal of neural transmission. - 129, 3 (2022) , 343-351, ISSN: 1435-1463
- Ereignis
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Veröffentlichung
- (wo)
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Freiburg
- (wer)
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Universität
- (wann)
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2022
- Urheber
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Ollmann, Theresa M.
Seidl, Esther
Venz, John
Pieper, Lars
Voss, Catharina
Hoyer, Jana
Kische, Hanna
Poppenhäger, S. R.
Schiele, Miriam A.
Domschke, Katharina
Beesdo-Baum, Katja
- DOI
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10.1007/s00702-022-02459-8
- URN
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urn:nbn:de:bsz:25-freidok-2256166
- Rechteinformation
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Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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25.03.2025, 13:46 MEZ
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Beteiligte
- Ollmann, Theresa M.
- Seidl, Esther
- Venz, John
- Pieper, Lars
- Voss, Catharina
- Hoyer, Jana
- Kische, Hanna
- Poppenhäger, S. R.
- Schiele, Miriam A.
- Domschke, Katharina
- Beesdo-Baum, Katja
- Universität
Entstanden
- 2022
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