Abeta Peptide and Alzheimer's Disease

Recent advances in genetics and brain biochemistry point to the Abeta peptide as the major culprit in causing neurodegeneration in Alzheimer's Disease (AD). Abeta Peptide and Alzheimer's Disease is specifically targeted at summarizing current knowledge of the Abeta peptide and its role in AD. Written by leaders in the industrial and academic world specializing in this rapidly moving area, the book covers fundamental biochemical studies on this peptide, the genetic impact on Abeta expression and processing, and various AD therapeutic strategies that target Abeta. Although specifically focusing on the Abeta peptide and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases, such as prion disease, Parkinsons and Huntingtons. This book will primarily be of interest to AD researchers and clinicians but also to researchers of other amyloid diseases. TOC:What spectroscopic studies of the Abeta peptide tell us about its role in AD - Abeta variants and there impact on amyloid formation and AD progression - Protofibrils and molecular mechanism of amyloid formation in AD - Neurotoxicity of Ab: Mechanisms and Consequences - Metal ions and their contribution of amyloid formation and Alzheimer's disease - Genetics and amyloid formation - Cholesterol and AD - Ab Immunization as a therapeutic strategy for the treatment of AD - Variations in APP processing and Alzheimer's disease - amyloid formation and neuronal degradation

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• ISBN: 1852339616
• Umfang: 208 S.
• Ausgabe: 1. Ed.
• Sprache: Englisch
• Anmerkungen: 70 schw.-w. Abb., 40 schw.-w. Fotos, 30 schw.-w. Zeichn.

Klassifikation und Themen

• Klassifikation: Medizin, Gesundheit

Beteiligte, Orts- und Zeitangaben

• Ereignis: Veröffentlichung
• (wo): Goldaming
• (wer): Springer London
• (wann): 2006
• Beteiligte Personen und Organisationen: Barrow, Colin J. ; Small, David H.

Weitere Informationen

• Inhaltsverzeichnis: https://d-nb.info/973272600/04
• Rechteinformation: Bei diesem Objekt liegt nur das Inhaltsverzeichnis digital vor. Der Zugriff darauf ist unbeschränkt möglich.
• Letzte Aktualisierung: 11.06.2025, 14:17 MESZ