Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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1 Online-Ressource.
- Language
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Englisch
- Bibliographic citation
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Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib ; volume:38 ; number:9 ; day:31 ; month:7 ; year:2024 ; pages:2046-2050 ; date:9.2024
Leukemia ; 38, Heft 9 (31.7.2024), 2046-2050, 9.2024
- Creator
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Leyte-Vidal, Ariel
DeFilippis, RosaAnna
Outhwaite, Ian R.
Kwan, Isabelle
Lee, Ji Young
Leavitt, Carlyn
Miller, Kaeli B.
Rea, Delphine
Rangwala, Aziz M.
Lou, Kevin
Patel, Suhana
Alvarez, Ailin
Shokat, Kevan M.
Bahar, Ivet
Seeliger, Markus A.
Shah, Neil P.
- Contributor
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SpringerLink (Online service)
- DOI
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10.1038/s41375-024-02353-0
- URN
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urn:nbn:de:101:1-2411112108335.392681902790
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:20 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Leyte-Vidal, Ariel
- DeFilippis, RosaAnna
- Outhwaite, Ian R.
- Kwan, Isabelle
- Lee, Ji Young
- Leavitt, Carlyn
- Miller, Kaeli B.
- Rea, Delphine
- Rangwala, Aziz M.
- Lou, Kevin
- Patel, Suhana
- Alvarez, Ailin
- Shokat, Kevan M.
- Bahar, Ivet
- Seeliger, Markus A.
- Shah, Neil P.
- SpringerLink (Online service)
Other Objects (12)
Genomische BCR-ABL1-Bruchpunkte bei kindlichen Leukämien
FISH mapping of Philadelphia negative BCR/ABL1 positive CML
Approach to Diagnosis of BCR::ABL1-Negative Myeloproliferative Neoplasms
BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene
Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells
Repurposing pexmetinib as an inhibitor of TKI-resistant BCR::ABL1
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy
The role of proteostasis in BCR-ABL1-positive acute lymphoblastic leukemia
SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells
Pre-B cell receptor signaling prevents malignant transformation by BCR-ABL1
Development of mirror-image monobodies targeting the oncogenic BCR::ABL1 kinase
Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K
Genomische BCR-ABL1-Bruchpunkte bei kindlichen Leukämien
FISH mapping of Philadelphia negative BCR/ABL1 positive CML
Approach to Diagnosis of BCR::ABL1-Negative Myeloproliferative Neoplasms
BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene
Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells
Repurposing pexmetinib as an inhibitor of TKI-resistant BCR::ABL1
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy
The role of proteostasis in BCR-ABL1-positive acute lymphoblastic leukemia
SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells
Pre-B cell receptor signaling prevents malignant transformation by BCR-ABL1
Development of mirror-image monobodies targeting the oncogenic BCR::ABL1 kinase
Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K
Genomische BCR-ABL1-Bruchpunkte bei kindlichen Leukämien
FISH mapping of Philadelphia negative BCR/ABL1 positive CML
Approach to Diagnosis of BCR::ABL1-Negative Myeloproliferative Neoplasms
BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene
Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells
Repurposing pexmetinib as an inhibitor of TKI-resistant BCR::ABL1
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy
The role of proteostasis in BCR-ABL1-positive acute lymphoblastic leukemia
SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells
Pre-B cell receptor signaling prevents malignant transformation by BCR-ABL1
Development of mirror-image monobodies targeting the oncogenic BCR::ABL1 kinase