Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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1 Online-Ressource.
- Sprache
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Englisch
- Erschienen in
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Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib ; volume:38 ; number:9 ; day:31 ; month:7 ; year:2024 ; pages:2046-2050 ; date:9.2024
Leukemia ; 38, Heft 9 (31.7.2024), 2046-2050, 9.2024
- Urheber
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Leyte-Vidal, Ariel
DeFilippis, RosaAnna
Outhwaite, Ian R.
Kwan, Isabelle
Lee, Ji Young
Leavitt, Carlyn
Miller, Kaeli B.
Rea, Delphine
Rangwala, Aziz M.
Lou, Kevin
Patel, Suhana
Alvarez, Ailin
Shokat, Kevan M.
Bahar, Ivet
Seeliger, Markus A.
Shah, Neil P.
- Beteiligte Personen und Organisationen
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SpringerLink (Online service)
- DOI
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10.1038/s41375-024-02353-0
- URN
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urn:nbn:de:101:1-2411112108335.392681902790
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:20 MESZ
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Beteiligte
- Leyte-Vidal, Ariel
- DeFilippis, RosaAnna
- Outhwaite, Ian R.
- Kwan, Isabelle
- Lee, Ji Young
- Leavitt, Carlyn
- Miller, Kaeli B.
- Rea, Delphine
- Rangwala, Aziz M.
- Lou, Kevin
- Patel, Suhana
- Alvarez, Ailin
- Shokat, Kevan M.
- Bahar, Ivet
- Seeliger, Markus A.
- Shah, Neil P.
- SpringerLink (Online service)
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FISH mapping of Philadelphia negative BCR/ABL1 positive CML
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BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene
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Repurposing pexmetinib as an inhibitor of TKI-resistant BCR::ABL1
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy
The role of proteostasis in BCR-ABL1-positive acute lymphoblastic leukemia
Pre-B cell receptor signaling prevents malignant transformation by BCR-ABL1
SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells
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