Urgent ERCP performed with single-use duodenoscope (SUD) in patients with moderate-to-severe cholangitis – a single-center prospective study.

Background. To assess the outcomes of urgent ERCP performed with single-use duodenoscope (SUD) in patients with moderate-to-severe cholangitis. Material and methods. Between 2021-2022 consecutive patients with moderate-to-severe cholangitis were prospectively enrolled to underwent urgent ERCP with SUD. Technical success was defined as the completion of planned procedure with SUD. Multivariate analysis was used to identify factors related to incidence of adverse events and mortality. Results. Thirty-five consecutive patients (15 female, age 81.4±6.7 years) were enrolled. Twelve (34.3%) had severe cholangitis; 26 (74.3%) were ASA≥3. Twenty-eight (80.0%) patients had a naïve papilla. Biliary sphincterotomy and complete steno stone clearance were performed in 29 (82.9%) and 30 (85.7%) patients, respectively; in 3 (8.6%) cases, concomitant EUS-gallbladder drainage was performed. Technical and clinical success rate were 100%. 30-day and 3-month mortality were 2.9% and 14.3%, respectively. One patient had mild post-ERCP pancreatitis and 2 delayed bleeding. No patients’ or procedural variables were related to adverse events. ASA score 4 and leucopenia were related to 3-month mortality; on multivariate analysis, leucopenia was the only variable independently related to 3-month mortality (odd ratio 12.8; 95% confidence interval 1.03 – 157.2; P 0.03). Conclusion. The results of this “proof of concept” study suggest that SUD use could be considered safe and effective for urgent ERCP for acute cholangitis. This approach abolishes duodenoscope contamination from infected patients without impairing clinical outcomes.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Urgent ERCP performed with single-use duodenoscope (SUD) in patients with moderate-to-severe cholangitis – a single-center prospective study. ; day:28 ; month:11 ; year:2023 ; Endoscopy International Open ; (28.11.2023)

Beteiligte, Orts- und Zeitangaben

• Beteiligte Personen und Organisationen: Masciangelo, Graziella ; Cecinato, Paolo ; Bacchilega, Igor ; Masetti, Michele ; Ferrari, Rodolfo ; Zagari, Rocco Maurizio ; Napoleon, Bertrand ; Sassatelli, Romano ; Fusaroli, Pietro ; Lisotti, Andrea

Weitere Informationen

• DOI: 10.1055/a-2219-0826
• URN: urn:nbn:de:101:1-2024011112090384582600
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 15.08.2025, 07:30 MESZ