Centre for statistical and methodological excellence (CESAME): a consortium initiative for improving methodology in randomised clinical trials
Abstract: When conducting randomised clinical trials, the choice of methodology and statistical analyses will influence the results. If the planned methodology is not of optimal quality and predefined in detail, there is a risk of biased trial results and interpretation. Even though clinical trial methodology is already at a very high standard, there are many trials that deliver biased results due to the implementation of inadequate methodology, poor data quality and erroneous or biased analyses. To increase the internal and external validity of randomised clinical trial results, several international institutions within clinical intervention research have formed The Centre for Statistical and Methodological Excellence (CESAME). Based on international consensus, the CESAME initiative will develop recommendations for the proper methodological planning, conduct and analysis of clinical intervention research. CESAME aims to increase the validity of randomised clinical trial results which will ultimately benefit patients worldwide across medical specialities. The work of CESAME will be performed within 3 closely interconnected pillars: (1) planning randomised clinical trials; (2) conducting randomised clinical trials; and (3) analysing randomised clinical trials
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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Health services insights. - 16 (2023) , 117863292311665, ISSN: 1178-6329
- Klassifikation
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Medizin, Gesundheit
- Ereignis
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Veröffentlichung
- (wo)
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Freiburg
- (wer)
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Universität
- (wann)
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2023
- Urheber
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Jørgensen, Caroline Kamp
Olsen, Markus Harboe
Nielsen, Niklas
Lange, Theis
Mbuagbaw, Lawrence
Thabane, Lehana
Billot, Laurent
Binder, Nadine
Garattini, Silvio
Banzi, Rita
Demotes, Jacques
Biagioli, Elena
Rulli, Eliana
Bertolini, Guido
Nattino, Giovanni
Mathiesen, Ole
Torri, Valter
Gluud, Christian
Jakobsen, Janus C.
- DOI
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10.1177/11786329231166519
- URN
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urn:nbn:de:bsz:25-freidok-2358077
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 10:57 MESZ
Datenpartner
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Beteiligte
- Jørgensen, Caroline Kamp
- Olsen, Markus Harboe
- Nielsen, Niklas
- Lange, Theis
- Mbuagbaw, Lawrence
- Thabane, Lehana
- Billot, Laurent
- Binder, Nadine
- Garattini, Silvio
- Banzi, Rita
- Demotes, Jacques
- Biagioli, Elena
- Rulli, Eliana
- Bertolini, Guido
- Nattino, Giovanni
- Mathiesen, Ole
- Torri, Valter
- Gluud, Christian
- Jakobsen, Janus C.
- Universität
Entstanden
- 2023
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