Microwave-assisted synthesis of bis (N -substituted thiazol-2-amine) derivatives and their biological activities

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Abstract: New 4,4′-(4,6-dimethoxy-1,3-phenylene)-bis (N-substituted thiazol-2-amine) derivatives 5a–j were synthesized from 1,1′-(4,6-dimethoxy-1,3-phenylene)-bis (2-bromoethanone) 3 and substituted thioureas 4a–j under conventional and microwave irradiation conditions. All products were subjected to in vitro antibacterial and anti-TB evaluation. Some of the compounds exhibit good activities against Bacillus subtilis (+ve), Escherichia coli (−ve) strains and Mycobacterium tuberculosis H37Rv.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Microwave-assisted synthesis of bis (N -substituted thiazol-2-amine) derivatives and their biological activities ; volume:23 ; number:5 ; year:2017 ; pages:405-409 ; extent:5
Heterocyclic communications ; 23, Heft 5 (2017), 405-409 (gesamt 5)

Urheber
Baba, N.H. Kumar
Ashok, D.
Rao, Boddu Ananda
Sarasija, Madderla
Murthy, N.Y.S.
Srinivasarao, Vankadari
Parthasarathy, Tigulla

DOI
10.1515/hc-2017-0129
URN
urn:nbn:de:101:1-2501140238309.132124325796
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:27 MESZ

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Beteiligte

  • Baba, N.H. Kumar
  • Ashok, D.
  • Rao, Boddu Ananda
  • Sarasija, Madderla
  • Murthy, N.Y.S.
  • Srinivasarao, Vankadari
  • Parthasarathy, Tigulla

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