Thyroid diseases are an underestimated risk factor for cerebral venous sinus thrombosis
Abstract: Introduction: Cerebral venous sinus thrombosis (CVST) is a rare disease that generally accounts for just 1% of all strokes. Of the multiple risk factors that have been identified, the most common are genetic or acquired thrombophilia and the use of oral contraceptives, while the less common include local infections and mechanical causes. Thyroid diseases have been described as rare risk factors for CVST (<2% of all cases), without exact knowledge of the underlying pathophysiology. This retrospective study aimed to re-evaluate the relevance of thyroid disease as risk factor for CVST, with particular emphasis on hyperthyroidism.
Patients and Methods: Confirmed cases of CVST were (re-)evaluated in terms of risk factors including thyroid parameters. Results were compared to previous data from the International Study on CVST.
Results: Between 1996 and 2016, 182 patients with confirmed CVST were treated in our hospital with a median age of 44 years and a female proportion of 74.7%. Genetic or acquired thrombophilia along with the use of oral contraceptives were found to be the most common risk factors. Thyroid diseases were present in 20.9% of CVST patients; this included patients with previous (9.9%) and current thyroid dysfunction (11%).
Discussion and Conclusions: Thyroid diseases may represent a more common risk factor for CVST than previously described. This holds true even if patients with current thyroid dysfunction are purely taken into account. However, 58% of patients had more than one additional risk factor, suggesting a multifactorial hypercoagulability
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Anmerkungen
-
Frontiers in neurology. - 11 (2020) , 561656, ISSN: 1664-2295
- Schlagwort
-
Risikofaktor
Hyperkoagulabilität
- Ereignis
-
Veröffentlichung
- (wo)
-
Freiburg
- (wer)
-
Universität
- (wann)
-
2020
- DOI
-
10.3389/fneur.2020.561656
- URN
-
urn:nbn:de:bsz:25-freidok-1696943
- Rechteinformation
-
Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
25.03.2025, 13:51 MEZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
Entstanden
- 2020
Ähnliche Objekte (12)
Handbook on cerebral venous thrombosis : 21 tables
![Posttraumatic cerebral venous sinus thrombosis: retrospective evaluation of risk factors, management and complications [Abstract]](/assets/placeholder/searchResultMediaUnknown.png)
Posttraumatic cerebral venous sinus thrombosis: retrospective evaluation of risk factors, management and complications [Abstract]
COVID-19 vaccine-associated cerebral venous thrombosis in Germany
COVID-19 Vaccine-Associated Cerebral Venous Thrombosis in Germany
Cerebral venous sinus thrombosis after ChAdOx1 nCov-19 vaccination with a misleading first cerebral MRI scan
Outcomes after decompressive surgery for severe cerebral venous sinus thrombosis associated or not associated with vaccine-induced Immune thrombosis with thrombocytopenia: a multicenter cohort study
Deep venous thrombosis and pulmonary embolism
Clinical value of neuroimaging indicators of intracranial hypertension in patients with cerebral venous thrombosis
Cerebral sinus thrombosis : experimental and clinical aspects ; [proceedings based on an International Symposium on Experimental and Clinical Aspects of Cerebral Sinus Thrombosis, held September 20 - 22, 1987, in Nymphenburg, Germany]
Infarct growth precedes cerebral thrombosis following experimental stroke in mice
Longterm results after surgical thrombectomy and simultaneous stenting for symptomatic iliofemoral venous thrombosis
The role of HIVEP1 in endothelial platelet interaction in the context of venous thrombosis
Handbook on cerebral venous thrombosis : 21 tables
Posttraumatic cerebral venous sinus thrombosis: retrospective evaluation of risk factors, management and complications [Abstract]
COVID-19 vaccine-associated cerebral venous thrombosis in Germany
COVID-19 Vaccine-Associated Cerebral Venous Thrombosis in Germany
Cerebral venous sinus thrombosis after ChAdOx1 nCov-19 vaccination with a misleading first cerebral MRI scan
Outcomes after decompressive surgery for severe cerebral venous sinus thrombosis associated or not associated with vaccine-induced Immune thrombosis with thrombocytopenia: a multicenter cohort study
Deep venous thrombosis and pulmonary embolism
Clinical value of neuroimaging indicators of intracranial hypertension in patients with cerebral venous thrombosis
Cerebral sinus thrombosis : experimental and clinical aspects ; [proceedings based on an International Symposium on Experimental and Clinical Aspects of Cerebral Sinus Thrombosis, held September 20 - 22, 1987, in Nymphenburg, Germany]
Infarct growth precedes cerebral thrombosis following experimental stroke in mice
Longterm results after surgical thrombectomy and simultaneous stenting for symptomatic iliofemoral venous thrombosis
The role of HIVEP1 in endothelial platelet interaction in the context of venous thrombosis
Handbook on cerebral venous thrombosis : 21 tables
Posttraumatic cerebral venous sinus thrombosis: retrospective evaluation of risk factors, management and complications [Abstract]
COVID-19 vaccine-associated cerebral venous thrombosis in Germany
COVID-19 Vaccine-Associated Cerebral Venous Thrombosis in Germany
Cerebral venous sinus thrombosis after ChAdOx1 nCov-19 vaccination with a misleading first cerebral MRI scan
Outcomes after decompressive surgery for severe cerebral venous sinus thrombosis associated or not associated with vaccine-induced Immune thrombosis with thrombocytopenia: a multicenter cohort study
Deep venous thrombosis and pulmonary embolism
Clinical value of neuroimaging indicators of intracranial hypertension in patients with cerebral venous thrombosis
Cerebral sinus thrombosis : experimental and clinical aspects ; [proceedings based on an International Symposium on Experimental and Clinical Aspects of Cerebral Sinus Thrombosis, held September 20 - 22, 1987, in Nymphenburg, Germany]
Infarct growth precedes cerebral thrombosis following experimental stroke in mice
Longterm results after surgical thrombectomy and simultaneous stenting for symptomatic iliofemoral venous thrombosis