Fourier transform temporal diffusion spectroscopy

Abstract: Temporal diffusion spectroscopy (TDS) currently uses the oscillating gradient spin echo (OGSE) experiment to measure the spectral density of translational velocity autocorrelation at single frequencies. Due to timing restrictions imposed by the transverse relaxation, the frequency selectivity and the sampling density of OGSE are limited, especially at low frequencies. We propose to overcome this problem by adopting the principles of Fourier transform spectroscopy. The new method of Fourier transform TDS (FTDS) uses two broadband gradient waveforms with different relative delays to make the spin echo attenuation sensitive to a broad range of diffusion frequencies with different harmonic modulations and calculates the spectrum by discrete Fourier transform. The method was validated by a measurement of diffusion spectra in highly restrictive tissues of a celery stalk and provided results consistent with OGSE, however, on a denser frequency grid

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch
Anmerkungen
Journal of magnetic resonance. - 348 (2023) , 107401, ISSN: 1090-7807

Ereignis
Veröffentlichung
(wo)
Freiburg
(wer)
Universität
(wann)
2023
Urheber

DOI
10.1016/j.jmr.2023.107401
URN
urn:nbn:de:bsz:25-freidok-2340688
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 10:56 MESZ

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  • 2023

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