Commonly Applied Selection Criteria for Lung Cancer Screening May Have Strongly Varying Diagnostic Performance in Different Countries
Abstract: Lung cancer (LC) screening often focuses heavy smokers as a target for screening group. Heavy smoking can thus be regarded as an LC pre-screening test with sensitivities and specificities being different in various populations due to the differences in smoking histories. We derive here expected sensitivities and specificities of various criteria to preselect individuals for LC screening in 27 European countries with diverse smoking prevalences. Sensitivities of various heavy-smoking-based pre-screening criteria were estimated by combining sex-specific proportions of people meeting these criteria in the target population for screening with associations of heavy smoking with LC risk. Expected specificities were approximated by the proportion of individuals not meeting the heavy smoking definition. Estimated sensitivities and specificities varied widely across countries, with sensitivities being generally higher among men (range: 33–80%) than among women (range: 9–79%), and specificit
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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Veröffentlichungsversion
begutachtet (peer reviewed)
In: Cancers ; 12 (2020) 10 ; 1-12
- Event
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Veröffentlichung
- (where)
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Mannheim
- (who)
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SSOAR, GESIS – Leibniz-Institut für Sozialwissenschaften e.V.
- (when)
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2020
- Creator
- DOI
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10.3390/cancers12103012
- URN
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urn:nbn:de:0168-ssoar-77811-1
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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25.03.2025, 1:50 PM CET
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Brenner, Hermann
- Krilaviciute, Agne
- SSOAR, GESIS – Leibniz-Institut für Sozialwissenschaften e.V.
Time of origin
- 2020
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Familial risk and risk-adapted starting age of screening in relatives of patients with prostate cancer
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Associations of vitamin D-binding protein, total, “non-bioavailable”, bioavailable, and free vitamin D, with mortality and type 2 diabetes
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