Biphasic parameter determination of sheep articular cartilage from stress relaxation data using an optimized 3D FE-based method

Abstract: Mechanical characteristics of hard and soft tissues are central features for the quantitative description of tissue properties. In this study, we present a biphasic 3D-FE-based method to determine the biomechanical properties of sheep stifle joint articular cartilage (load-bearing area of the medial and lateral femur condyle, n = 28) from stress relaxation indentation tests (s = 0.1 mm, t = 180 s). The FE-model computation was optimized by exploiting the axial symmetry and mesh resolution. Parameters were determined using the Levenberg-Marquardt-algorithm. Results showed significant differences between the biomechanical parameters of the lateral (n = 11) and medial (n = 17) femur condyle of the sheep stifle joint articular cartilage. R² of the fit results varied between 0.91 and 0.99. Overall values for the Young’s modulus were 1.316 ± 0.778 MPa, for the Poisson’s ratio 0.106 ± 0.088 and for the permeability 0.008 ± 0.004 mm4/Ns. Future work will focus on studying the influence of experimental settings on the results obtained with the biphasic 3D-FE-model.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Biphasic parameter determination of sheep articular cartilage from stress relaxation data using an optimized 3D FE-based method ; volume:9 ; number:1 ; year:2023 ; pages:383-386 ; extent:4 ; Current directions in biomedical engineering ; 9, Heft 1 (2023), 383-386 (gesamt 4)

Beteiligte, Orts- und Zeitangaben

• Urheber: Reuter, Thomas ; Horbert, Victoria ; Kinne, Raimund W. ; Hurschler, Christof

Weitere Informationen

• DOI: 10.1515/cdbme-2023-1096
• URN: urn:nbn:de:101:1-2023092214080103281629
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 14.08.2025, 11:03 MESZ