Nicolau Syndrome after Intramuscular Injection: 3 Cases
Nicolau syndrome is a rare complication of intramuscular injection consisting of ischemic necrosis of skin, soft tissue, and muscular tissue that arises locoregionally. The characteristic pattern is pain around the injection site, developing into erythema, a livedoid dermatitis patch, and necrosis of the skin, subcutaneous fat, and muscle tissue. Three patients were injected with drugs (diclofenac sodium, ketoprofen, meperidine) for pain relief. Three patients complained of pain, and a skin lesion was observed, after which necrosis developed on their buttocks. Each patient underwent debridement and coverage. The wound healed uneventfully. We report three cases of Nicolau syndrome in the buttocks following diclofenac intramuscular injection.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Nicolau Syndrome after Intramuscular Injection: 3 Cases ; volume:39 ; number:03 ; year:2012 ; pages:249-252
Archives of Plastic Surgery ; 39, Heft 03 (2012), 249-252
- Contributor
-
Kim, Seok-Kwun
Kim, Tae-Heon
Lee, Keun-Cheol
- DOI
-
10.5999/aps.2012.39.3.249
- URN
-
urn:nbn:de:101:1-2022061610184165933134
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:32 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Kim, Seok-Kwun
- Kim, Tae-Heon
- Lee, Keun-Cheol
Other Objects (12)
Tissue Damage Caused by Diclofenac Intramuscular Injection: The Nicolau Syndrome
Nicolau Syndrome: An Unforeseen Yet Evadable Consequence of Intramuscular Injection
In vitro simulation of distribution processes following intramuscular injection
Gastric endoscopic muscularis dissection using a partial intramuscular injection technique
Iatrogenic Infection of Clostridium welchii Following Intramuscular Injection of Sodium Diclofenac
Oestradiol-17β plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas (Lama glama)
Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud syndrome
Nicolau syndrome due to diclofenac sodium (Voltaren®) injection: a case report
Rubus occidentalis alleviates hyperalgesia induced by repeated intramuscular injection of acidic saline in rats
Vapocoolant Spray for Pain Control in Intramuscular Injection Applications: A Prospective, Randomized Controlled Trial
Piezo-surgery technique and intramuscular dexamethasone injection to reduce postoperative pain after impacted mandibular third molar surgery: a randomized clinical trial
Effectiveness of intramuscular corticosteroid injection versus placebo injection in patients with hip osteoarthritis: design of a randomized double-blinded controlled trial
Tissue Damage Caused by Diclofenac Intramuscular Injection: The Nicolau Syndrome
Nicolau Syndrome: An Unforeseen Yet Evadable Consequence of Intramuscular Injection
In vitro simulation of distribution processes following intramuscular injection
Gastric endoscopic muscularis dissection using a partial intramuscular injection technique
Iatrogenic Infection of Clostridium welchii Following Intramuscular Injection of Sodium Diclofenac
Oestradiol-17β plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas (Lama glama)
Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud syndrome
Nicolau syndrome due to diclofenac sodium (Voltaren®) injection: a case report
Rubus occidentalis alleviates hyperalgesia induced by repeated intramuscular injection of acidic saline in rats
Vapocoolant Spray for Pain Control in Intramuscular Injection Applications: A Prospective, Randomized Controlled Trial
Piezo-surgery technique and intramuscular dexamethasone injection to reduce postoperative pain after impacted mandibular third molar surgery: a randomized clinical trial
Effectiveness of intramuscular corticosteroid injection versus placebo injection in patients with hip osteoarthritis: design of a randomized double-blinded controlled trial
Tissue Damage Caused by Diclofenac Intramuscular Injection: The Nicolau Syndrome
Nicolau Syndrome: An Unforeseen Yet Evadable Consequence of Intramuscular Injection
In vitro simulation of distribution processes following intramuscular injection
Gastric endoscopic muscularis dissection using a partial intramuscular injection technique
Iatrogenic Infection of Clostridium welchii Following Intramuscular Injection of Sodium Diclofenac
Oestradiol-17β plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas (Lama glama)
Polyostotic fibrous dysplasia associated with intramuscular myxomas: Mazabraud syndrome
Nicolau syndrome due to diclofenac sodium (Voltaren®) injection: a case report
Rubus occidentalis alleviates hyperalgesia induced by repeated intramuscular injection of acidic saline in rats
Vapocoolant Spray for Pain Control in Intramuscular Injection Applications: A Prospective, Randomized Controlled Trial
Piezo-surgery technique and intramuscular dexamethasone injection to reduce postoperative pain after impacted mandibular third molar surgery: a randomized clinical trial