Tissue Damage Caused by Diclofenac Intramuscular Injection: The Nicolau Syndrome

Abstract: Introduction Nicolau syndrome is an extremely rare complication following intramuscular administration of drugs leading to tissue damage and necrosis. Case Report In this case, the patient received the injection from an untrained quack surgeon (Jarrah) due to an improper intramuscular injection technique. A 45-year-old female complained of pain and blackish discoloration of the skin over the left buttock after receiving an intramuscular diclofenac injection.4 The patient was managed by administering intravenous antibiotics and analgesics, followed by surgical debridement. Flap reconstruction was done after granulation tissue formation. Conclusion Healthcare should be sought from appropriately trained and licensed professionals. Patients should be well educated on this. Pain, erythema, and discoloration should be recognized as red flags of the Nicolau syndrome so that it can be addressed promptly to avoid complications.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Tissue Damage Caused by Diclofenac Intramuscular Injection: The Nicolau Syndrome ; day:23 ; month:02 ; year:2023
Ibnosina journal of medicine and biomedical sciences ; (23.02.2023)

Beteiligte Personen und Organisationen
Anees, Afzal
Hassan, Yaqoob
Motiwala, Zainab Yusufali
Khan, Isna Rafat

DOI
10.1055/s-0043-1761214
URN
urn:nbn:de:101:1-2023041310181144057854
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
14.08.2025, 11:00 MESZ

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Beteiligte

  • Anees, Afzal
  • Hassan, Yaqoob
  • Motiwala, Zainab Yusufali
  • Khan, Isna Rafat

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