Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin

Abstract: A concise and efficient total synthesis of the lignan natural product larreatricin as well as an unambiguous assignment of configuration of its enantiomers are reported, resolving a long‐held controversy. Enzyme kinetic studies revealed that different polyphenol oxidases show high and remarkably divergent enantioselective recognition of this secondary metabolite.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin ; volume:24 ; number:59 ; year:2018 ; pages:15756-15760 ; extent:5
Chemistry - a European journal ; 24, Heft 59 (2018), 15756-15760 (gesamt 5)

Creator
Martin, Harry J.
Kampatsikas, Ioannis
Oost, Rik
Pretzler, Matthias
Al‐Sayed, Emir
Roller, Alexander
Giester, Gerald
Rompel, Annette
Maulide, Nuno

DOI
10.1002/chem.201803785
URN
urn:nbn:de:101:1-2022082008165998535323
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:26 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Associated

Other Objects (12)