Molecular basis and clonal evolution of myeloproliferative neoplasms

to related objects

Abstract: Myeloproliferative neoplasms (MPNs) represent a group of diseases that affect the myeloid lineage, characterized by the presence of an excess of terminally differentiated myeloid cells. Defects causing clonal hematopoiesis are a key factor in the emergence of these diseases. Throughout the years, a number of causative defects have been identified, predominantly affecting cytokine signaling and gene expression regulation. This review aims to provide an update on the current status of the MPN field in relation to identification of molecular defects involved in the disease and its clonal evolution.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Molecular basis and clonal evolution of myeloproliferative neoplasms ; volume:51 ; number:10 ; year:2013 ; pages:1889-1896 ; extent:8
Clinical chemistry and laboratory medicine ; 51, Heft 10 (2013), 1889-1896 (gesamt 8)

Creator
Cleary, Ciara
Kralovics, Robert

DOI
10.1515/cclm-2013-0135
URN
urn:nbn:de:101:1-2022061115121722551672
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:38 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Show original at data provider

Associated

  • Cleary, Ciara
  • Kralovics, Robert

Other Objects (12)

Mutation patterns and clonal evolution in myeloproliferative neoplasms

Mutation patterns and clonal evolution in myeloproliferative neoplasms

Renal disease associated with myeloproliferative neoplasms and myelodysplastic syndrome/myeloproliferative neoplasms

Renal disease associated with myeloproliferative neoplasms and myelodysplastic syndrome/myeloproliferative neoplasms

Renal disease associated with myeloproliferative neoplasms and myelodysplastic syndrome/myeloproliferative neoplasms

Renal disease associated with myeloproliferative neoplasms and myelodysplastic syndrome/myeloproliferative neoplasms

Targeted therapies for myeloproliferative neoplasms

Targeted therapies for myeloproliferative neoplasms

Esophageal lesions in myeloproliferative neoplasms

Esophageal lesions in myeloproliferative neoplasms

Novel therapeutics in myeloproliferative neoplasms

Novel therapeutics in myeloproliferative neoplasms

Renal post-mortem findings in myeloproliferative and myelodysplastic/myeloproliferative neoplasms

Renal post-mortem findings in myeloproliferative and myelodysplastic/myeloproliferative neoplasms

New mouse models of myeloproliferative neoplasms

Hochschulschrift

New mouse models of myeloproliferative neoplasms

Myeloproliferative neoplasms : critical concepts and management

Aufsatzsammlung

Myeloproliferative neoplasms : critical concepts and management

SRSF2 mutations in myelodysplasia/myeloproliferative neoplasms

SRSF2 mutations in myelodysplasia/myeloproliferative neoplasms

Myeloproliferative neoplasms: cause, mechanism and treatment

Myeloproliferative neoplasms: cause, mechanism and treatment

Molecular pathogenesis of the myeloproliferative neoplasms

Molecular pathogenesis of the myeloproliferative neoplasms

Related objects