Implementing pharmacogenomic clinical decision support into German hospitals

Abstract: Background: Pharmacogenomic Clinical Decision Support Systems (CDSS) are considered to be the most feasible tool for adopting pharmacogenomic testing into clinical routine.

Objective: To discuss important factors for implementing pharmacogenomic CDSS into German hospitals.

Methods: We analyzed two relevant studies. Furthermore, we interviewed data privacy officers of three German university hospitals and examined relevant legal regulations in literature.

Results: There are three major barriers for implementing pharmacogenomic CDSS into German hospitals: (i) the legal uncertainty; (ii) the lack of machine-readable data; (iii) the remaining knowledge gap of both genetics and pharmacogenomics among physicians.

Conclusion: The implementation of passive clinical decision support (CDS) for somatic mutations in the form of structured pharmacogenomic reports might be the most feasible CDS feature for clinicians in German hospitals

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Studies in health technology and informatics. - 247 (2018) , 870 - 874, ISSN: 1879-8365

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2019
Creator
Contributor
Zentrum für Biochemie und Molekulare Zellforschung
Arbeitsgruppe Medizinische Informatik

DOI
10.3233/978-1-61499-852-5-870
URN
urn:nbn:de:bsz:25-freidok-1444609
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
25.03.2025, 1:50 PM CET

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Associated

Time of origin

  • 2019

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