Implementing pharmacogenomic clinical decision support into German hospitals
Abstract: Background: Pharmacogenomic Clinical Decision Support Systems (CDSS) are considered to be the most feasible tool for adopting pharmacogenomic testing into clinical routine.
Objective: To discuss important factors for implementing pharmacogenomic CDSS into German hospitals.
Methods: We analyzed two relevant studies. Furthermore, we interviewed data privacy officers of three German university hospitals and examined relevant legal regulations in literature.
Results: There are three major barriers for implementing pharmacogenomic CDSS into German hospitals: (i) the legal uncertainty; (ii) the lack of machine-readable data; (iii) the remaining knowledge gap of both genetics and pharmacogenomics among physicians.
Conclusion: The implementation of passive clinical decision support (CDS) for somatic mutations in the form of structured pharmacogenomic reports might be the most feasible CDS feature for clinicians in German hospitals
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Notes
-
Studies in health technology and informatics. - 247 (2018) , 870 - 874, ISSN: 1879-8365
- Event
-
Veröffentlichung
- (where)
-
Freiburg
- (who)
-
Universität
- (when)
-
2019
- Creator
-
Hinderer, Marc
Börries, Melanie
Boeker, Martin
Neumaier, Michael
Loubal, Frank-Peter
Acker, Till
Brunner, Manfred
Prokosch, Hans-Ulrich
Christoph, Jan
- Contributor
-
Zentrum für Biochemie und Molekulare Zellforschung
Arbeitsgruppe Medizinische Informatik
- DOI
-
10.3233/978-1-61499-852-5-870
- URN
-
urn:nbn:de:bsz:25-freidok-1444609
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
25.03.2025, 1:50 PM CET
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Hinderer, Marc
- Börries, Melanie
- Boeker, Martin
- Neumaier, Michael
- Loubal, Frank-Peter
- Acker, Till
- Brunner, Manfred
- Prokosch, Hans-Ulrich
- Christoph, Jan
- Zentrum für Biochemie und Molekulare Zellforschung
- Arbeitsgruppe Medizinische Informatik
- Universität
Time of origin
- 2019