Fragmentbasiertes Design von p97-Liganden: Identifizierung von Startstrukturen zur Entwicklung von Protein-Protein-Interaktionsinhibitoren für die SHP-Bindestelle der AAA+ ATPase p97
- Weitere Titel
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Fragment-based design of p97-ligands: Identification of starting points for the development of protein-protein-interaction inhibitors targeting the SHP-binding site of the AAA+ ATPase p97
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Deutsch
- Anmerkungen
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Würzburg, Universität Würzburg, Dissertation, 2021
- Schlagwort
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Proteine
Bindestelle
Inhibitor
Ligand
Arzneimitteldesign
Wirkstoffdesign
- Ereignis
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Veröffentlichung
- (wo)
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Würzburg
- (wer)
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Universität Würzburg
- (wann)
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2021
- Urheber
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Bothe, Sebastian
- Beteiligte Personen und Organisationen
- DOI
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10.25972/OPUS-23911
- URN
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urn:nbn:de:bvb:20-opus-239112
- Rechteinformation
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
14.08.2025, 10:57 MESZ
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Beteiligte
- Bothe, Sebastian
- Sotriffer, Christoph
- Schindelin, Hermann
- Universität Würzburg
Entstanden
- 2021
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The AAA-ATPase p97 in mitosis and fertilization
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Die UBX-Domäne von UBXD1 organisiert die Ubiquitinbindung am C-Terminus der AAA-ATPase VCP/p97 zum proteasomalen Abbau
UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97
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Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97
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