Electrosynthesis of Quinoxalines via Intermolecular Cyclization/Dehydrogenation of Ketones with o-Phenylenediamines
In this study, we proposed a novel electrochemical dehydrogenative synthetic method for preparing 2-substituted quinoxalines by intermolecular cyclization of aryl alkyl ketones and o-phenylenediamines. This method gave various quinoxalines in yields ranging from 35% to 71%. This novel protocol employs mild reaction conditions and offers moderate to excellent yields, a wide substrate scope, and broad functional-group compatibility. Furthermore, a late-stage functionalization and the wide substrate scope demonstrated the synthetic utility of this protocol.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Electrosynthesis of Quinoxalines via Intermolecular Cyclization/Dehydrogenation of Ketones with o-Phenylenediamines ; day:14 ; month:06 ; year:2024
Synlett ; (14.06.2024)
- Beteiligte Personen und Organisationen
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Tao, Yi
Zhang, Jiahui
Hu, Yangyang
Liu, Huiying
Sun, Jingwen
Liu, Lei
- DOI
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10.1055/a-2339-2832
- URN
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urn:nbn:de:101:1-2408221143184.154721649207
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 10:45 MESZ
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Beteiligte
- Tao, Yi
- Zhang, Jiahui
- Hu, Yangyang
- Liu, Huiying
- Sun, Jingwen
- Liu, Lei
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