Jamaican fruit bats mount a stable and highly neutralizing antibody response after bat influenza virus infection
Abstract: Antibodies are an essential component of the antiviral response in many species, but to date, there is no compelling evidence that bats are capable of eliciting a robust humoral immunity, including neutralizing antibodies. Here, we report that infection of Jamaican fruit bats with the bat influenza A virus H18N11 elicits a rapid and stable humoral immune response with a strong neutralizing capacity, associated with no detectable viral shedding after repeat challenge infection. Thus, the neutralizing antibody response of bats might play an important role in the bat immunity
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Anmerkungen
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Proceedings of the National Academy of Sciences of the United States of America. - 121, 42 (2024) , e2413619121, ISSN: 1091-6490
- Ereignis
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Veröffentlichung
- (wo)
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Freiburg
- (wer)
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Universität
- (wann)
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2024
- Urheber
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Kessler, Susanne
Stegen, Philipp
Zhan, Shijun
Schwemmle, Martin
Reuther, Peter
Schountz, Tony
Ciminski, Kevin
- DOI
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10.1073/pnas.2413619121
- URN
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urn:nbn:de:bsz:25-freidok-2576012
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:21 MESZ
Datenpartner
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Beteiligte
- Kessler, Susanne
- Stegen, Philipp
- Zhan, Shijun
- Schwemmle, Martin
- Reuther, Peter
- Schountz, Tony
- Ciminski, Kevin
- Universität
Entstanden
- 2024