Jamaican fruit bats mount a stable and highly neutralizing antibody response after bat influenza virus infection
Abstract: Antibodies are an essential component of the antiviral response in many species, but to date, there is no compelling evidence that bats are capable of eliciting a robust humoral immunity, including neutralizing antibodies. Here, we report that infection of Jamaican fruit bats with the bat influenza A virus H18N11 elicits a rapid and stable humoral immune response with a strong neutralizing capacity, associated with no detectable viral shedding after repeat challenge infection. Thus, the neutralizing antibody response of bats might play an important role in the bat immunity
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Notes
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Proceedings of the National Academy of Sciences of the United States of America. - 121, 42 (2024) , e2413619121, ISSN: 1091-6490
- Event
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Veröffentlichung
- (where)
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Freiburg
- (who)
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Universität
- (when)
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2024
- Creator
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Kessler, Susanne
Stegen, Philipp
Zhan, Shijun
Schwemmle, Martin
Reuther, Peter
Schountz, Tony
Ciminski, Kevin
- DOI
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10.1073/pnas.2413619121
- URN
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urn:nbn:de:bsz:25-freidok-2576012
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:21 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Kessler, Susanne
- Stegen, Philipp
- Zhan, Shijun
- Schwemmle, Martin
- Reuther, Peter
- Schountz, Tony
- Ciminski, Kevin
- Universität
Time of origin
- 2024
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