Dirichlet composition distribution for compositional data with zero components: An application to fluorescence in situ hybridization (FISH) detection of chromosome
Abstract: Zeros in compositional data are very common and can be classified into rounded and essential zeros. The rounded zero refers to a small proportion or below detection limit value, while the essential zero refers to the complete absence of the component in the composition. In this article, we propose a new framework for analyzing compositional data with zero entries by introducing a stochastic representation. In particular, a new distribution, namely the Dirichlet composition distribution, is developed to accommodate the possible essential‐zero feature in compositional data. We derive its distributional properties (e.g., its moments). The calculation of maximum likelihood estimates via the Expectation‐Maximization (EM) algorithm will be proposed. The regression model based on the new Dirichlet composition distribution will be considered. Simulation studies are conducted to evaluate the performance of the proposed methodologies. Finally, our method is employed to analyze a dataset of fluorescence in situ hybridization (FISH) for chromosome detection.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Dirichlet composition distribution for compositional data with zero components: An application to fluorescence in situ hybridization (FISH) detection of chromosome ; day:16 ; month:12 ; year:2021 ; extent:19
Biometrical journal ; (16.12.2021) (gesamt 19)
- Creator
-
Tang, Man‐Lai
Wu, Qin
Yang, Sheng
Tian, Guo‐Liang
- DOI
-
10.1002/bimj.202000334
- URN
-
urn:nbn:de:101:1-2021121714134595032598
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:23 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Tang, Man‐Lai
- Wu, Qin
- Yang, Sheng
- Tian, Guo‐Liang
Other Objects (12)
Comparative analysis of Corynebacterium glutamicum genomes: a new perspective for the industrial production of amino acids
SRT-Server: powering the analysis of spatial transcriptomic data
circ_CHFR regulates ox-LDL-mediated cell proliferation, apoptosis, and EndoMT by miR-15a-5p/EGFR axis in human brain microvessel endothelial cells
Emerging 2D Materials Produced via Electrochemistry
Prognostic evaluation models for primary thyroid lymphoma, based on the SEER database and an external validation cohort
ρ − ω mixing contribution to the measured CP asymmetry of B ± → ωK ±
Fault traceability of power grid dispatching system based on DPHS-MDS and LambdaMART algorithm
View suggestion for interactive segmentation of indoor scenes
Mass-Spring-Damping Theory Based Equivalent Mechanical Model for Cylindrical Lithium-ion Batteries under Mechanical Abuse
Identifying and exploiting gene-pathway interactions from RNA-seq data for binary phenotype
Lactate dehydrogenase elevations is associated with severity of COVID-19: a meta-analysis
Association of sun-seeking behaviors with indoor tanning behavior in US white females during high school/college in Nurses’ Health Study II
Comparative analysis of Corynebacterium glutamicum genomes: a new perspective for the industrial production of amino acids
SRT-Server: powering the analysis of spatial transcriptomic data
circ_CHFR regulates ox-LDL-mediated cell proliferation, apoptosis, and EndoMT by miR-15a-5p/EGFR axis in human brain microvessel endothelial cells
Emerging 2D Materials Produced via Electrochemistry
Prognostic evaluation models for primary thyroid lymphoma, based on the SEER database and an external validation cohort
ρ − ω mixing contribution to the measured CP asymmetry of B ± → ωK ±
Fault traceability of power grid dispatching system based on DPHS-MDS and LambdaMART algorithm
View suggestion for interactive segmentation of indoor scenes
Mass-Spring-Damping Theory Based Equivalent Mechanical Model for Cylindrical Lithium-ion Batteries under Mechanical Abuse
Identifying and exploiting gene-pathway interactions from RNA-seq data for binary phenotype
Lactate dehydrogenase elevations is associated with severity of COVID-19: a meta-analysis
Association of sun-seeking behaviors with indoor tanning behavior in US white females during high school/college in Nurses’ Health Study II
Comparative analysis of Corynebacterium glutamicum genomes: a new perspective for the industrial production of amino acids
SRT-Server: powering the analysis of spatial transcriptomic data
circ_CHFR regulates ox-LDL-mediated cell proliferation, apoptosis, and EndoMT by miR-15a-5p/EGFR axis in human brain microvessel endothelial cells
Emerging 2D Materials Produced via Electrochemistry
Prognostic evaluation models for primary thyroid lymphoma, based on the SEER database and an external validation cohort
ρ − ω mixing contribution to the measured CP asymmetry of B ± → ωK ±
Fault traceability of power grid dispatching system based on DPHS-MDS and LambdaMART algorithm
View suggestion for interactive segmentation of indoor scenes
Mass-Spring-Damping Theory Based Equivalent Mechanical Model for Cylindrical Lithium-ion Batteries under Mechanical Abuse
Identifying and exploiting gene-pathway interactions from RNA-seq data for binary phenotype
Lactate dehydrogenase elevations is associated with severity of COVID-19: a meta-analysis