Progress in Nanotechnology for Treating Ocular Surface Chemical Injuries: Reflecting on Advances in Ophthalmology

Abstract: Ocular surface chemical injuries often result in permanent visual impairment and necessitate complex, long‐term treatments. Immediate and extensive irrigation serves as the first‐line intervention, followed by various therapeutic protocols applied throughout different stages of the condition. To optimize outcomes, conventional regimens increasingly incorporate biological agents and surgical techniques. In recent years, nanotechnology has made significant strides, revolutionizing the management of ocular surface chemical injuries by enabling sustained drug release, enhancing treatment efficacy, and minimizing side effects. This review provides a comprehensive analysis of the etiology, epidemiology, classification, and conventional therapies for ocular chemical burns, with a special focus on nanotechnology‐based drug delivery systems in managing ocular surface chemical injuries. Twelve categories of nanocarrier platforms are examined, including liposomes, nanoemulsions, nanomicelles, nanowafers, nanostructured lipid carriers, nanoparticles, hydrogels, dendrimers, nanocomplexes, nanofibers, nanozymes, and nanocomposite materials, highlighting their advantages in targeted delivery, biocompatibility, and improved healing efficacy. Additionally, current challenges and limitations in the field are discussed and the future potential of nanotechnology in treating ocular diseases is explored. This review presents the most extensive examination of this topic to date, aiming to link recent advancements with broader therapeutic strategies.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Progress in Nanotechnology for Treating Ocular Surface Chemical Injuries: Reflecting on Advances in Ophthalmology ; day:04 ; month:01 ; year:2025 ; extent:70
Advanced science ; (04.01.2025) (gesamt 70)

Creator
Qi, Qiaoran
Su, Dai
Zhuang, Shuqin
Yao, Sunyuan
Heindl, Ludwig M.
Fan, Xianqun
Lin, Ming
Li, Jin
Pang, Yan

DOI
10.1002/advs.202407340
URN
urn:nbn:de:101:1-2501051304108.104528030366
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:35 AM CEST

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Associated

  • Qi, Qiaoran
  • Su, Dai
  • Zhuang, Shuqin
  • Yao, Sunyuan
  • Heindl, Ludwig M.
  • Fan, Xianqun
  • Lin, Ming
  • Li, Jin
  • Pang, Yan

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