Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1471-2407

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer ; volume:16 ; number:1 ; day:2 ; month:8 ; year:2016 ; pages:1-16 ; date:12.2016
BMC cancer ; 16, Heft 1 (2.8.2016), 1-16, 12.2016

Creator: She, Qing-Bai

Contributor: Gruvberger-Saal, Sofia K.
Maurer, Matthew
Chen, Yilun
Jumppanen, Mervi
Su, Tao
Dendy, Meaghan
Lau, Ying-Ka Ingar
Memeo, Lorenzo
Horlings, Hugo M.
van de Vijver, Marc J.
Isola, Jorma
Hibshoosh, Hanina
Rosen, Neal
Parsons, Ramon
Saal, Lao H.
SpringerLink (Online service)

DOI: 10.1186/s12885-016-2609-2

URN: urn:nbn:de:1111-201608041146

Rights: Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:58 AM CEST

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Associated

She, Qing-Bai
Gruvberger-Saal, Sofia K.
Maurer, Matthew
Chen, Yilun
Jumppanen, Mervi
Su, Tao
Dendy, Meaghan
Lau, Ying-Ka Ingar
Memeo, Lorenzo
Horlings, Hugo M.
van de Vijver, Marc J.
Isola, Jorma
Hibshoosh, Hanina
Rosen, Neal
Parsons, Ramon
Saal, Lao H.
SpringerLink (Online service)

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Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer

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Other Objects (12)

Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer

Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells

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Targeted Pten deletion plus p53-R270H mutation in mouse mammary epithelium induces aggressive claudin-low and basal-like breast cancer

Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas

Weight loss reduces basal-like breast cancer through kinome reprogramming

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The CD44+/CD24-phenotype is enriched in basal-like breast tumors

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ME1 promotes basal-like breast cancer progression and associates with poor prognosis

Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer

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Gene expression signatures of morphologically normal breast tissue identify basal-like tumors

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