A Pd‐Catalyzed Annulation Strategy to Linearly Fused Functionalized N‐Heterocycles
Abstract: Linearly fused polycyclic piperidines represent common substructures in natural products and biologically active small molecules. We have devised a Pd‐catalyzed annulation strategy to these compounds that converts readily available 2‐tetralones and indanones into these scaffolds with the potential for control of both enantio‐ and diastereoselectivity. Importantly, these compounds can be chemoselectively functionalized, providing an efficient and robust methodology to these important nitrogen‐containing molecules.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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A Pd‐Catalyzed Annulation Strategy to Linearly Fused Functionalized N‐Heterocycles ; day:20 ; month:02 ; year:2024 ; extent:7
Chemistry - a European journal ; (20.02.2024) (gesamt 7)
- Creator
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Hoteite, Larry
Allen, Benjamin D. W.
Elhajj, Ms. Ergaiya A.
Meijer, Anthony J. H. M.
Harrity, Joseph P. A.
- DOI
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10.1002/chem.202400116
- URN
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urn:nbn:de:101:1-2024022114591797827266
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 11:01 AM CEST
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Hoteite, Larry
- Allen, Benjamin D. W.
- Elhajj, Ms. Ergaiya A.
- Meijer, Anthony J. H. M.
- Harrity, Joseph P. A.
Other Objects (12)
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Stereoselectively fluorinated N-heterocycles: a brief survey
Electrochemical access to biologically potent five-membered N-heterocycles
Photodehydrogenation of N-Heterocycles with Hexagonal Boron Carbon Nitride
Polyfunctionalizations of N-heterocycles via chemo- and regioselective metalations
Iron(II)‐Catalyzed Aerobic Biomimetic Oxidation of N‐Heterocycles
A sustainable thermochemical conversion of animal biomass to N-heterocycles
Synthesis of Saturated N‐Heterocycles via a Catalytic Hydrogenation Cascade
Bifunctional sulfilimines enable synthesis of multiple N-heterocycles from alkenes
Bifunctional sulfilimines enable synthesis of multiple N-heterocycles from alkenes
Turning Carbocycles into N-Heterocycles by Cobalt-Catalyzed Nitrogen Atom Insertion
Pd‐Catalyzed (3+2)‐Dehydrogenative Annulation Reactions
Aziridines Cross-Dimerize to Larger N-Heterocycles
Stereoselectively fluorinated N-heterocycles: a brief survey
Electrochemical access to biologically potent five-membered N-heterocycles
Photodehydrogenation of N-Heterocycles with Hexagonal Boron Carbon Nitride
Polyfunctionalizations of N-heterocycles via chemo- and regioselective metalations
Iron(II)‐Catalyzed Aerobic Biomimetic Oxidation of N‐Heterocycles
A sustainable thermochemical conversion of animal biomass to N-heterocycles
Synthesis of Saturated N‐Heterocycles via a Catalytic Hydrogenation Cascade
Bifunctional sulfilimines enable synthesis of multiple N-heterocycles from alkenes
Bifunctional sulfilimines enable synthesis of multiple N-heterocycles from alkenes
Turning Carbocycles into N-Heterocycles by Cobalt-Catalyzed Nitrogen Atom Insertion
Pd‐Catalyzed (3+2)‐Dehydrogenative Annulation Reactions
Aziridines Cross-Dimerize to Larger N-Heterocycles
Stereoselectively fluorinated N-heterocycles: a brief survey
Electrochemical access to biologically potent five-membered N-heterocycles
Photodehydrogenation of N-Heterocycles with Hexagonal Boron Carbon Nitride
Polyfunctionalizations of N-heterocycles via chemo- and regioselective metalations
Iron(II)‐Catalyzed Aerobic Biomimetic Oxidation of N‐Heterocycles
A sustainable thermochemical conversion of animal biomass to N-heterocycles
Synthesis of Saturated N‐Heterocycles via a Catalytic Hydrogenation Cascade
Bifunctional sulfilimines enable synthesis of multiple N-heterocycles from alkenes
Bifunctional sulfilimines enable synthesis of multiple N-heterocycles from alkenes