Accelerated Degradation of polymeric surgical suture materials

Abstract: The degradable polymer Polydioxanone (PDO) is used for medical implants since 1981. Manufacturers state a degradation timeframe of <180 days or an absorption duration of 182-238 days [1, 2]. Aim of this study was to find in vitro-conditions to degrade PDO films within four weeks. Therefore the degradation of PDO was performed in accelerated conditions in tempered alkaline glycine NaOH buffer. Molecular weight and mass loss were studied. PDO results were compared with poly lactic-co-glycolic acid P (LLA-co-GA).

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Accelerated Degradation of polymeric surgical suture materials ; volume:6 ; number:3 ; year:2020 ; pages:458-460 ; extent:3
Current directions in biomedical engineering ; 6, Heft 3 (2020), 458-460 (gesamt 3)

Creator
Reske, Thomas
Eickner, Thomas
Grabow, Niels
Schmitz, Klaus-Peter
Siewert, Stefan

DOI
10.1515/cdbme-2020-3118
URN
urn:nbn:de:101:1-2022101215162396411351
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.11.2025, 2:21 PM CET

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Associated

  • Reske, Thomas
  • Eickner, Thomas
  • Grabow, Niels
  • Schmitz, Klaus-Peter
  • Siewert, Stefan

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