Therapeutic potential of bioactive compounds from Punica granatum extracts against aging and complicity of FOXO orthologue DAF-16 in Caenorhabditis elegans

Abstract: Some natural fruits have significant importance in improving health which provides many nutritional supplements essential to maintain proper metabolism with the age. In this study, phytochemical screening of extract (methanolic) of Punica granatum arils, outer and inner peels was confirmed by the respective spot tests. Quantification of phytochemical constituents revealed the plentiful of total phenols in the outer peels in comparison to inner peels and juice whereas total flavonoids and vitamin C are abundant in inner peel and juice, respectively. High-performance liquid chromatography, Gas chromatography along with mass spectrometry and Fourier-transform infrared spectroscopy analysis revealed the presence of compound 9, 17-octadecadienal, (Z) in the outer/inner peels. A compound N-hexadecanoic acid was also observed in the outer peels. Extracts from every section of the fruits were comprehensively evaluated for their antioxidant activity. Contrary to fruit aril juice, the extrac.... https://www.excli.de/index.php/excli/article/view/3011

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Therapeutic potential of bioactive compounds from Punica granatum extracts against aging and complicity of FOXO orthologue DAF-16 in Caenorhabditis elegans ; volume:20 ; day:11 ; month:01 ; year:2021 ; EXCLI journal ; 20 (11.01.2021)

Contributors, Places and Time

• Creator: Chaubey, Mukesh Ghanshyam ; Chauhan, Anita P. ; Chokshi, Pooja R. ; Amin, Rahi S. ; Patel, Stuti N. ; Madamwar, Datta ; Rastogi, Rajesh P. ; Singh, Niraj Kumar

Further information

• DOI: 10.17179/excli2020-3011
• URN: urn:nbn:de:101:1-2021051813361055963314
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:48 AM CEST