Development of the SupersonicIEF Method for High‐Throughput Charge Variant Analysis
Abstract: The analysis of biopharmaceuticals for charge variants occurs from early‐stage samples through formulation and process‐development optimization. Higher throughput methods allow increased analysis of these samples to facilitate greater understanding of the samples and to better optimize their production and formulation. To enable higher throughput charge variant analysis, a new, rapid platform imaged capillary isoelectric focusing (icIEF) method was optimized to be two to three times faster than standard methods.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Development of the SupersonicIEF Method for High‐Throughput Charge Variant Analysis ; day:14 ; month:10 ; year:2024 ; extent:8
Electrophoresis ; (14.10.2024) (gesamt 8)
- Urheber
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McElroy, Will
Heger, Christopher D.
- DOI
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10.1002/elps.202400117
- URN
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urn:nbn:de:101:1-2410151435195.370697986529
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:34 MESZ
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Beteiligte
- McElroy, Will
- Heger, Christopher D.
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